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News Archive2022-05-17T18:07:20+00:00

News Archive

  • Pitt School of Dental Medicine Goes Opioid-Free

    Categories: Epidemiology, News ArchivePublished On: December 4, 2019

    The University of Pittsburgh School of Dental Medicine is the first in the nation to establish opioid-free pain management guidelines for the vast majority of procedures performed in all of its clinics. For decades, opioid pain relievers have been routinely prescribed for dental procedures, including the surgical extraction of wisdom teeth – often a teenager’s first exposure to opioids. Since current evidence shows that alternative, non-opioid medications generally work as well or even better for managing pain after dental work, without the side effects of nausea, vomiting, constipation and potential for misuse, Pitt Dental Medicine has developed a set of [...]

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  • Researchers Find New Role for Dopamine in Gene Transcription and Cell Proliferation

    Categories: Cellular Therapy, News ArchivePublished On: December 4, 2019

    The dopamine D2 receptor has a previously unobserved role in modulating Wnt expression and control of cell proliferation, according to a new study from the George Washington University (GW) and the University of Pittsburgh. The research, published in Scientific Reports, could have implications for the development of new therapeutics across multiple disciplines including nephrology, endocrinology, and psychiatry.  Zachary Freyberg, MD, PhD, an assistant professor of psychiatry and cell biology at the University of Pittsburgh School of Medicine and an affiliated faculty member of the McGowan Institute for Regenerative Medicine, is a senior author on the study. Dopamine is traditionally studied [...]

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  • Weber Lab Student Clinches First Place at SHPE Poster Competition

    Categories: Awards and Recognition, News ArchivePublished On: December 4, 2019

    Sebastian Correa, a junior bioengineering student in the lab of McGowan Institute for Regenerative Medicine affiliated faculty member Douglas Weber, PhD, associate professor in the Department of Bioengineering at the University of Pittsburgh and director of the Rehab Neural Engineering Labs (RNEL), attended the Society of Hispanic Professional Engineers (SHPE) National Convention in Phoenix and received the first place award at the Engineering Science Symposium poster competition. Mr. Correa presented a poster on using a high-density electromyography (HDEMG) electrode sleeve array to analyze surface EMG from individuals who have sustained spinal cord injury. “We use the HDEMG sleeve to record [...]

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  • Review Article Provides a Framework for Ongoing/Future Brain Tissue Healing Studies

    Categories: Neuroscience, News Archive, Tissue EngineeringPublished On: November 20, 2019

    Some of the most challenging medical conditions are acute brain injury and progressive neurodegenerative disease.  Aiming to examine these issues, Frontiers in Neuroscience recently published the review article entitled “Bioscaffold-Induced Brain Tissue Regeneration” by Michel Modo, PhD, Professor in the Department of Radiology at the University of Pittsburgh with secondary appointments in the Department of Bioengineering and the Center for Neural Basis of Cognition. Dr. Modo writes, “Although little is currently known about mechanisms involved in brain tissue regeneration, this review outlines the various components and their interplay to provide a framework for ongoing and future studies. It is envisaged [...]

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  • Metastatic Breast Cancer Research Receives A Glimmer of Hope Foundation Funding

    Categories: Cancer, Cellular Therapy, Epidemiology, News ArchivePublished On: November 20, 2019

    Magee-Womens Research Institute (MWRI) has received $112,500 in funding from A Glimmer of Hope Foundation (GOH) to further research of metastatic breast cancer (MBC) and to enhance patient support services at UPMC Magee-Womens Hospital. “We are grateful to A Glimmer of Hope Foundation for supporting our research efforts,” said McGowan Institute for Regenerative Medicine affiliated faculty member Steffi Oesterreich, PhD, director, Women’s Cancer Research Center at MWRI and UPMC Hillman Cancer Center. “This funding will help us to measure patient response to treatment and identify changes that may have emerged during tumor evolution.” The use of solid tumor biopsies — [...]

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  • Pitt Team’s Replacement Heart Valve Could Decrease Need for Pediatric Surgeries

    Categories: Medical Devices, News ArchivePublished On: November 13, 2019

    Garrett Coyan, MD, sees many patients each week, from children to the elderly, to check on their replacement heart valves. “We have to counsel patients every day on which current technology is right for them, including what medicine they need to take and what limitations they have for their lifestyle,” said Dr. Coyan, a resident in the University of Pittsburgh’s six-year integrated cardiothoracic surgery residency program and a team member in the lab of McGowan Institute for Regenerative Medicine director, William Wagner, PhD. “It can be hard to do sometimes.” Heart valve disease affects over 2.5% of the US population, [...]

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  • Dr. Tracy Cui Leads Pitt Neuron Research in Pitt/CMU Brain Collaboration

    Categories: Medical Devices, Neuroscience, News ArchivePublished On: November 13, 2019

    The brain is a complex organ full of neurons that work together to help us move, feel, think, and more. A multidisciplinary group from the University of Pittsburgh (Pitt) and Carnegie Mellon University (CMU) is working to expand the amount of information researchers can receive from a neural interface device and received two grants from the National Science Foundation (NSF) for their collaborative effort. The team, headed by CMU’s Maysam Chamanzar, PhD, plans to develop an all-in-one implantable device that can simultaneously record neural activity, identify the cell type, and determine cell function through chemical stimulation. More information about these [...]

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  • Dr. Dobrawa Napierala Awarded Grant to Commemorate Soft Bones 10th Anniversary and Hypophosphatasia Awareness Day

    Categories: Cellular Therapy, News ArchivePublished On: November 13, 2019

    To commemorate Hypophosphatasia Awareness Day (October 30), Soft Bones, Inc., an organization dedicated to providing information, education and support to those affected by hypophosphatasia (HPP), awarded its tenth annual Maher Family Grant.  In commemoration of its tenth anniversary, Soft Bones awarded two grants for the first time ever.  McGowan Institute for Regenerative Medicine affiliated faculty member Dobrawa Napierala, PhD, Associate Professor of Oral Biology at the Center for Craniofacial Regeneration, University of Pittsburgh School of Dental Medicine, is one of this year’s awardees and will study adolescents and adults with HPP. Dr. Napierala will address the novel role of tissue-nonspecific [...]

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