Stegemann JP, Wagner WR, Göbel U, Perets E, Leong KW, Leach JK, Gilbert J. The Year 2022 in biomaterials research: A perspective from the editors of six leading journals. J Biomed Mater Res A. 2023 Mar 23. doi: 10.1002/jbm.a.37529. Online ahead of print.

Behrangzade A, Keeney HR, Martinet KM, Wagner WR, Vande Geest JP. Mechanical alterations of electrospun poly(ε-caprolactone) in response to convective thermobonding. J Biomed Mater Res B Appl Biomater. 2023 Mar;111(3):622-632. doi: 10.1002/jbm.b.35181. Epub 2022 Oct 11. PMID: 36221771.

Emery SP, Greene S, Elsisy M, Chung K, Ye SH, Kim S, Wagner WR, Hazen N, Chun Y. In vitro and in vivo assessment of a novel ultra-flexible ventriculoamniotic shunt for treating fetal hydrocephalus. 2023 Mar;37(8):1423-1435. doi: 10.1177/08853282221125309. Epub 2022 Sep 5. PMID: 36063383.

Behrangzade A, Simon BR, Wagner WR, Geest JPV. Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning. J Biomech Eng. 2023 Feb 1;145(2):021002. doi: 10.1115/1.4055563. PMID: 36082481.

Kim S, Nowicki KW, Ye S, Jang K, Elsisy M, Ibrahim M, Chun Y, Gross BA, Friedlander RM, Wagner WR. Bioabsorbable, elastomer-coated magnesium alloy coils for treating saccular cerebrovascular aneurysms. Biomaterials. 2022 Nov;290:121857. doi: 10.1016/j.biomaterials.2022.121857. Epub 2022 Oct 17. PMID: 36326510.

Pedersen DD, Kim S, Wagner WR. Biodegradable polyurethane scaffolds in regenerative medicine: Clinical translation review. J Biomed Mater Res A. 2022 Aug;110(8):1460-1487. doi: 10.1002/jbm.a.37394. Epub 2022 Apr 28. PMID: 35481723.

Furdella KJ, Higuchi S, Kim K, Doetschman T, Wagner WR, Vande Geest JP. Acute Elution of TGFΒ2 Affects the Smooth Muscle Cells in a Compliance-Matched Vascular Graft. Tissue Eng Part A. 2022 Jul;28(13-14):640-650. doi: 10.1089/ten.TEA.2021.0161. PMID: 35521649; PMCID: PMC9354035.

Adamo A, Bartolacci JG, Pedersen DD, Traina MG, Kim S, Pantano A, Ghersi G, Watkins SC, Wagner WR, Badylak SF, D’Amore A. Continuous Microfiber Wire Mandrel-Less Biofabrication for Soft Tissue Engineering Applications. Adv Healthc Mater. 2022 Jul;11(13):e2102613. doi: 10.1002/adhm.202102613. Epub 2022 Apr 29. PMID: 35394654.

Nguyen-Truong M, Kim S, Doherty C, Frederes M, LeBar K, Ghosh S, Hematti P, Chinnadurai R, Wagner WR, Wang Z. Pro-angiogenic Potential of Mesenchymal Stromal Cells Regulated by Matrix Stiffness and Anisotropy Mimicking Right Ventricles. Biomacromolecules. 2022 Jun 13;23(6):2353-2361. doi: 10.1021/acs.biomac.2c00132. Epub 2022 May 3. PMID: 35502841.

Luketich SK, Cosentino F, Di Giuseppe M, Menallo G, Nasello G, Livreri P, Wagner WR, D’Amore A. Engineering in-plane mechanics of electrospun polyurethane scaffolds for cardiovascular tissue applications. J Mech Behav Biomed Mater. 2022 Apr;128:105126. doi: 10.1016/j.jmbbm.2022.105126. Epub 2022 Feb 12. PMID: 35180648.

Adamo A, Bruno A, Menallo G, Francipane MG, Fazzari M, Pirrone R, Ardizzone E, Wagner WR, D’Amore A. Blood Vessel Detection Algorithm for Tissue Engineering and Quantitative Histology. Ann Biomed Eng. 2022 Apr;50(4):387-400. doi: 10.1007/s10439-022-02923-2. Epub 2022 Feb 16. PMID: 35171393; PMCID: PMC8917109.

Mercader A, Ye SH, Kim S, Orizondo RA, Cho SK, Wagner WR. PDMS-Zwitterionic Hybrid for Facile, Antifouling Microfluidic Device Fabrication. Langmuir. 2022 Mar 29;38(12):3775-3784. doi: 10.1021/acs.langmuir.1c03375. Epub 2022 Mar 16. PMID: 35294197.

Sharma A, Clemens RA, Garcia O, Taylor DL, Wagner NL, Shepard KA, Gupta A, Malany S, Grodzinsky AJ, Kearns-Jonker M, Mair DB, Kim DH, Roberts MS, Loring JF, Hu J, Warren LE, Eenmaa S, Bozada J, Paljug E, Roth M, Taylor DP, Rodrigue G, Cantini P, Smith AW, Giulianotti MA, Wagner WR. Biomanufacturing in low Earth orbit for regenerative medicine. Stem Cell Reports. 2022 Jan 11;17(1):1-13. doi: 10.1016/j.stemcr.2021.12.001. Epub 2021 Dec 30. PMID: 34971562; PMCID: PMC8758939.

Kim S, Nowicki KW, Gross BA, Wagner WR. Injectable hydrogels for vascular embolization and cell delivery: The potential for advances in cerebral aneurysm treatment. Biomaterials. 2021 Oct;277:121109. doi: 10.1016/j.biomaterials.2021.121109. Epub 2021 Aug 31. PMID: 34530233.

Taylor DP, Yoshida M, Fuller K, Giannobile WV, Sfeir CS, Wagner WR, Kohn DH. Translating Dental, Oral, and Craniofacial Regenerative Medicine Innovations to the Clinic through Interdisciplinary Commercial Translation Architecture. J Dent Res. 2021 Sep;100(10):1039-1046. doi: 10.1177/00220345211009502. Epub 2021 Apr 27. PMID: 33906502.

Silveira-Filho LM, Coyan GN, Adamo A, Luketich SK, Menallo G, D’Amore A, Wagner WR. Can a Biohybrid Patch Salvage Ventricular Function at a Late Time Point in the Post-Infarction Remodeling Process? JACC Basic Transl Sci. 2021 Mar 24;6(5):447-463. doi: 10.1016/j.jacbts.2021.01.004. eCollection 2021 May. PMID: 34095634.

Kawakami Y, Nonaka K, Fukase N, Amore A, Murata Y, Quinn P, Luketich S, Takayama K, Patel KG, Matsumoto T, Cummins JH, Kurosaka M, Kuroda R, Wagner WR, Fu FH, Huard J. A Cell-free Biodegradable Synthetic Artificial Ligament for the Reconstruction of Anterior Cruciate Ligament in a Rat Model. Acta Biomater. 2021 Feb;121:275-287.

Furdella KJ, Higuchi S, Behrangzade A, Kim K, Wagner WR, Vande Geest JP.. In vivo assessment of a tissue engineered vascular graft computationally optimized for target vessel compliance. Acta Biomater. 2021 Jan 20:S1742-7061(21)00019-2.

Wu J, Mady LJ, Roy A, Aral AM, Lee B, Zheng F, Catalin T, Chun Y, Wagner WR, Yang K, Trejo Bittar HE, Chi D, Kumta PN. In-vivo efficacy of biodegradable ultrahigh ductility Mg-Li-Zn alloy tracheal stents for pediatric airway obstruction. Commun Biol. 2020 Dec 18;3(1):787.

Cunnane EM, Lorentz KL, Soletti L, Ramaswamy AK, Chung TK, Haskett DG, Luketich SK, Tzeng E, D’Amore A, Wagner WR, Weinbaum JS, Vorp DA. Development of a Semi-Automated, Bulk Seeding Device for Large Animal Model Implantation of Tissue Engineered Vascular Grafts. Front Bioeng Biotechnol. 2020 Oct 23;8:597847.

Orizondo RA, Omecinski KS, May AG, Dhamotharan V, Frankowski BJ, Burgreen GW, Ye SH, Kocyildirim E, Sanchez PG, D’Cunha J, Wagner WR, Federspiel WJ. Month-long Respiratory Support by a Wearable Pumping Artificial Lung in an Ovine Model. Transplantation. 2020 Oct 7.

May AG, Orizondo RA, Frankowski BJ, Ye SH, Kocyildirim E, Wagner WR, D’Cunha J, Federspiel WJ. In vivo testing of the low-flow CO2 removal application of a compact, platform respiratory device. Intensive Care Med Exp. 2020 Aug 17;8(1):45.

Kim S, Ye SH, Adamo A, Orizondo RA, Jo J, Cho SK, Wagner WR. A biostable, anti-fouling zwitterionic polyurethane-urea based on PDMS for use in blood-contacting medical devices. Mater Chem B. 2020 Sep 23;8(36):8305-8314.

Kashiyama N, Kormos RL, Matsumura Y, D’Amore A, Miyagawa S, Sawa Y, Wagner WR. Adipose-derived stem cell sheet under an elastic patch improves cardiac function in rats after myocardial infarction. J Thorac Cardiovasc Surg. 2020 May 18:S0022-5223(20)31139-9.

Coyan GN, da Mota Silveira-Filho L, Matsumura Y, Luketich SK, Katz W, Badhwar V, Wagner WR, D’Amore A. Acute In Vivo Functional Assessment of a Biodegradable Stentless Elastomeric Tricuspid Valve. J Cardiovasc Transl Res. 2020 Oct;13(5):796-805.

Valencia-Rivero, KT, Cruz JC, Wagner-Gutierrez N, D’Amore A, Miranda MC, Lopez R, Guerrero A, Wagner W, Sandoval N, Briceño JC. Evaluation of Microscopic Structure−Function Relationships of PEGylated Small Intestinal Submucosa Vascular Grafts for Arteriovenous Connection. ACS Appl Bio Mater. 2, 9, 3706-3721 (2019).

Willett NJ, Boninger ML, Miller LJ, Alvarez L, Aoyama T, Bedoni M, Brix KA, Chisari C, Christ G, Dearth CL, Dyson-Hudson TA, Evans CH, Goldman SM, Gregory K, Gualerzi A, Hart J, Ito A, Kuroki H, Loghmani MT, Mack DL, Malanga GA, Noble- Haeusslein L, Pasquina P, Roche JA, Rose L, Stoddart MJ, Tajino J, Terzic C, Topp KS, Wagner WR, Warden SJ, Wolf SL, Xie H, Rando TA, Ambrosio F. Taking the Next Steps in Regenerative Rehabilitation: Establishment of a New Interdisciplinary Field. Arch Phys Med Rehabil. 2020 May;101(5):917-923.

Valencia-Rivero, KT, Cruz JC, Wagner-Gutierrez N, D’Amore A, Miranda MC, Lopez R, Guerrero A, Wagner W, Sandoval N, Briceño JC. Evaluation of Microscopic Structure−Function Relationships of PEGylated Small Intestinal Submucosa Vascular Grafts for Arteriovenous Connection. ACS Appl Bio Mater. 2, 9, 3706-3721 (2019).

Matsumura Y, Zhu Y, Jiang H, D’Amore A, Luketich SK, Charwat V, Yoshizumi T, Sato H, Yang B, Uchibori T, Healy KE, Wagner WR. Intramyocardial injection of a fully synthetic hydrogel attenuates left ventricular remodeling post myocardial infarction. Biomaterials. 17;217:119289. (2019).

Simon MA, Bachman TN, Watson J, Baldwin JT, Wagner WR, Borovetz HS. Current and Future Considerations in the Use of Mechanical Circulatory Support Devices: An Update, 2008-2018. Annu Rev Biomed Eng. 4;21:33-60. (2019).

D’Amore A, Luketich SK, Hoff R, Ye SH, Wagner WR. Blending polymer lavile elements at differing scales to affect degradation profiles in heart valve scaffolds. Biomacromolecules. 20(7):2494-2505. (2019).

Ardila DC, Tamimi E, Doetschman T, Wagner WR, Vande Geest JP. Modulating smooth muscle cell response by the release of TGFβ2 from tubular scaffolds for vascular tissue engineering. J Control Release. 299:44-52 (2019).

Ardila DC, Liou JJ, Maestas D, Slepian MJ, Badowski M, Wagner WR, Harris D, Vande Geest JP. Surface modification of electrospun scaffolds for endothelialization of tissue-engineered vascular grafts using human cord blood-derived endothelial cells. J Clin Med. 8:E185 (2019).

Coyan GN, D’Amore A, Matsumura Y, Pedersen DD, Luketich SK, Shanov V, Katz WE, David TE, Wagner WR, Badhwar V. In vivo functional assessment of a novel degradable metal and elastomeric scaffold-based tissue engineered heart valve. J Thorac Cardiovasc Surg. 157(5):1809-16. (2019).

Sivaraman S, Amoroso N, Gu X, Purves JT, Hughes FM Jr, Wagner WR, Nagatomi J. Evaluation of poly (carbonate-urethane) urea (PCUU) scaffolds for urinary bladder tissue engineering. Ann Biomed Eng. 47:891-901 (2019).

Ye SH, Chen Y, Mao Z, Gu X, Shankarraman V, Hong Y, Shanov V, Wagner WR. Biodegradable zwitterionic polymer coatings for magnesium alloy stents. Langmuir. 35:1421-9 (2019).

Pocivavsek L, Ye SH, Pugar J, Tzeng E, Cerda E, Velankar S, Wagner WR. Active wrinkles to drive self-cleaning: A strategy for anti-thrombotic surfaces for vascular grafts. Biomaterials. Nov 5;192:226-234. (2018).

Haskett DG, Saleh KS, Lorentz KL, Josowitz AD, Luketich SK, Weinbaum JS, Kokai LE, D’Amore A, Marra KG, Rubin JP, Wagner WR, Vorp DA. An exploratory study on the preparation and evaluation of a “same-day” adipose stem cell-based tissue-engineered vascular graft. J Thorac Cardiovasc Surg. Nov 156(5):1814-1822.e3. (2018).

D’Amore A, Nasello G, Luketich SK, Denisenko D, Jacobs DL, Hoff R, Gibson G, Bruno A, T Raimondi M, Wagner WR. Meso-scale topological cues influence extracellular matrix production in a large deformation, elastomeric scaffold model. Soft Matter. Oct 24. doi: 10.1039/c8sm01352g. (2018).

Liu L, Ye SH, Gu X, Russell T, Xu Z, Sankar J, Wagner WR, Lee YC, Yun Y. Comparison of endothelial cell attachment on surfaces of biodegradable polymer-coated magnesium alloys in a microfluidic environment. PLoS One. Oct 10;13(10): e0205611. (2018).

Johnson CA Jr, Woolley JR, Snyder TA, Shankarraman V, Haney EI, Wagner WR. Assessment of Thrombelastography and Platelet Life Span in Ovines. Artif Organs. Sep 25. doi: 10.1111/aor.13282 (2018).

Howe C, Mishra S, Kim YS, Chen Y, Ye SH, Wagner WR, Jeong JW, Byun HS, Kim JH, Chun Y, Yeo WH. Stretchable, Implantable, Nanostructured Flow-Diverter System for Quantification of Intra-aneurysmal Hemodynamics. ACS Nano. Jul 20. (2018).

Schuh CA, Hono K, Wagner WR, Gault B, D’Angelo J, Gray GT Editorial: 3rd Launching Materialia. Acta Biomater. Jul 15; 75:1-2. (2018).

Zhu Y, Matsumura Y, Velayutham M, Foley LM, Hitchens TK, Wagner WR. Reactive oxygen species scavenging with a biodegradable, thermally responsive hydrogel compatible with soft tissue injection. Biomaterials. 177:98-112. (2018).

Olia SE, Wearden PD, Maul TM, Shankarraman V, Kocyildirim E, Snyder ST, Callahan PM, Kameneva MV, Wagner WR, Borovetz HS, Antaki JF. Preclinical performance of a pediatric mechanical circulatory support device: The PediaFlow ventricular assist device. J Thorac Cardiovasc Surg. (2018).

Chen Y, Ye SH, Sato H, Zhu Y, Shanov V, Tiasha T, D’Amore A, Luketich S, Wan G, Wagner WR. Hybrid scaffolds of Mg alloy mesh reinforced polymer/extracellular matrix composite for critical-sized calvarial defect reconstruction. J Tissue Eng Regen Med. 12(6):1374-1388. (2018).

Zhu Y, Hideyoshi S, Jiang H, Matsumura Y, Dziki JL, LoPresti ST, Huleihel L, Faria GNF, Fuhrman LC, Lodono R, Badylak SF, Wagner WR. Injectable, porous, biohybrid hydrogels incorporating decellularized tissue components for soft tissue applications. Acta Biomater. 73:112-126. (2018).

Giannobile WV, Chai Y, Chen Y, Healy KE, Klein O, Lane N, Longaker MT, Lotz JC, Mooney DJ, Sfeir CS, Urata M, Wagner WR, Wu BM, Kohn DH. Dental, Oral, and Craniofacial Regenerative Medicine: Transforming Biotechnologies for Innovating Patient Care. J Dent Res. 97(4):361-363. (2018).

Malkin AD, Ye SH, Lee EJ, Yang X, Zhu Y, Gamble LJ, Federspiel WJ, Wagner WR. Development of zwitterionic sulfobetaine block copolymer conjugation strategies for reduced platelet deposition in respiratory assist devices. J Biomed Mater Res B Appl Biomater. Feb 9. (2018).

Madhani SP, Frankowski BJ, Ye SH, Burgreen GW, Wagner WR, Kormos R, D’Cunha J, Federspiel WJ. In Vivo 5 Day Animal Studies of a Compact, Wearable Pumping Artificial Lung. ASAIO J. 2017 Dec 11.

van der Merwe Y, Faust AE, Conner I, Gu X, Feturi F, Zhao W, Leonard B, Roy S, Gorantla VS, Venkataramanan R, Washington KM, Wagner WR, Steketee MB. An Elastomeric Polymer Matrix, PEUU-Tac, Delivers Bioactive Tacrolimus Transdurally to the CNS in Rat. EBioMedicine. 2017 Dec:26:47-59.

D’Amore A, Fazzari M, Jiang HB, Luketich SK, Luketich ME, Hoff R, Jacobs DL, Gu X, Badylak SF, Freeman BA, Wagner WR. Nitro-Oleic Acid (NO(2)-OA) Release Enhances Regional Angiogenesis in a Rat Abdominal Wall Defect Model. Tissue Eng Part A. 24(11-12):889-904. (2018).

D’Amore A, Luketich SK, Raffa GM, Olia S, Menallo G, Mazzola A, D’Accardi F, Grunberg T, Gu X, Pilato M, Kameneva MV, Badhwar V, Wagner WR. Heart valve scaffold fabrication: Bioinspired control of macro-scale morphology, mechanics and micro-structure. Biomaterials. 150:25-37. (2018).

Schuh CA, Hono K, Wagner WR, Gault B, D’Angelo J, Gray GT 3rd. Paths to Open Access: An update from Acta Materialia, Inc. Acta Biomater. 15;60:1-2. (2017).

Uchibori T, Takanari K, Hashizume R, Amoroso NJ, Kamei Y, Wagner WR. Use of a pedicled omental flap to reduce inflammation and vascularize an abdominal wall patch. J Surg Res. 5;212:77-85. (2017).

Chun Y, Cho SK, Clark WC, Wagner WR, Gu X, Tevar AD, McEnaney RM, Tillman BW. A retrievable rescue stent graft and radiofrequency positioning for rapid control of noncompressible hemorrhage. J Trauma Acute Care Surg. 2017 Aug;83(2):249-255.

Gu X, Matsumura Y, Tang Y, Roy S, Hoff R, Wang B, Wagner WR. Sustained viral gene delivery from a micro-fibrous, elastomeric cardiac patch to the ischemic rat heart. Biomaterials. 133:132-143. (2017).

Stearns-Reider KM, D’Amore A, Beezhold K, Rothrauff B, Cavalli L, Wagner WR, Vorp DA, Tsamis A, Shinde S, Zhang C, Barchowsky A, Rando TA, Tuan RS, Ambrosio F. Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion. Aging Cell. 2017 Jun;16(3):518-528.

Zhu Y, Matsumura Y, Wagner WR. Ventricular wall biomaterial injection therapy after myocardial infarction: Advances in material design, mechanistic insight and early clinical experiences. Biomaterials. 2017 Jun;129:37-53.

Wu WT, Jamiolkowski MA, Wagner WR, Aubry N, Massoudi M, Antaki JF. Multi-Constituent Simulation of Thrombus Deposition. Sci Rep. 2017 Feb 20;7:42720.

Wang J, Qin B, Chen X, Wagner WR, Villanueva FS. Ultrasound Molecular Imaging of Angiogenesis Using Vascular Endothelial Growth Factor-Conjugated Microbubbles. Mol Pharm. 2017 Mar 6;14(3):781-790.

Krawiec JT, Liao HT, Kwan LL, D’Amore A, Weinbaum JS, Rubin JP, Wagner WR, Vorp DA. Evaluation of the stromal vascular fraction of adipose tissue as the basis for a stem cell-based tissue-engineered vascular graft. J Vasc Surg. 2017 Sep;66(3):883-890.e1.

Takanari K, Hashizume R, Hong Y, Amoroso NJ, Yoshizumi T, Gharaibeh B, Yoshida O, Nonaka K, Sato H, Huard J, Wagner WR. Skeletal muscle derived stem cells microintegrated into a biodegradable elastomer for reconstruction of the abdominal wall. Biomaterials. 2017 113:31-41.

Chen Y, Tillman BW, Cho SK, Richards TD, Tevar AD, Gu X, Wagner WR, Chun Y. A novel compartmentalised stent graft to isolate the perfusion of the abdominal organs. J Med Eng Technol. 2017 Feb;41(2):141-150.

D’Amore A, Yoshizumi T, Luketich SK, Wolf MT, Gu X, Cammarata M, Hoff R, Badylak SF, Wagner WR. Bi-layered polyurethane – Extracellular matrix cardiac patch improves ischemic ventricular wall remodeling in a rat model. Biomaterials. 2016 107:1-14.

Tillman BW, Chun Y, Cho SK, Chen Y, Liang N, Maul T, Demetris A, Gu X, Wagner WR, Tevar AD. Dual chamber stent prevents organ malperfusion in a model of donation after cardiac death. Surgery. 2016 Oct;160(4):892-901.

D’Amore A, Soares JS, Stella JA, Zhang W, Amoroso NJ, Mayer JE Jr, Wagner WR, Sacks MS. Large strain stimulation promotes extracellular matrix production and stiffness in an elastomeric scaffold model. J Mech Behav Biomed Mater. 2016 Sep; 62:619-635.

Fang J, Zhang J, Du J, Pan Y, Shi J, Peng Y, Chen W, Yuan L, Ye SH, Wagner WR, Yin M, Mo X. Orthogonally Functionalizable Polyurethane with Subsequent Modification with Heparin and Endothelium-Inducing Peptide Aiming for Vascular Reconstruction. ACS Appl Mater Interfaces. 8(23):14442-14452 (2016).

Jamiolkowski MA, Pedersen DD, Wu WT, Antaki JF, Wagner WR. Visualization and analysis of biomaterial-centered thrombus formation within a defined crevice under flow. Biomaterials. 96:72-83 (2016).

Zhu Y, Wood NA, Fok K, Yoshizumi T, Park DW, Jiang H, Schwartzman DS, Zenati MA, Uchibori T, Wagner WR, Riviere CN. Design of a Coupled Thermoresponsive Hydrogel and Robotic System for Postinfarct Biomaterial Injection Therapy. Ann Thorac Surg. pii: S0003-4975(16)00267-8 (2016).

Gu X, Mao Z, Ye SH, Koo Y, Yun Y, Tiasha TR, Shanov V, Wagner WR. Biodegradable, elastomeric coatings with controlled anti-proliferative agent release for magnesium-based cardiovascular stents. Colloids Surf B Biointerfaces. 144:170-9 (2016).

Krawiec JT, Weinbaum JS, Liao HT, Ramaswamy AK, Pezzone DJ, Josowitz AD, D’Amore A, Rubin JP, Wagner WR, Vorp DA. In Vivo Functional Evaluation of Tissue-Engineered Vascular Grafts Fabricated Using Human Adipose-Derived Stem Cells from High Cardiovascular Risk Populations. Tissue Eng Part A. 22(9-10):765-75 (2016).

Chen Y, Emery SP, Maxey AP, Gu X, Wagner WR, Chun Y. A novel low-profile ventriculoamniotic shunt for foetal aqueductal stenosis. J Med Eng Technol. 40(4):186-98 (2016).

Tsamis A, Phillippi JA, Koch RG, Chan PG, Krawiec JT, D’Amore A, Watkins SC, Wagner WR, Vorp DA, Gleason TG. Extracellular matrix fiber microarchitecture is region-specific in bicuspid aortic valve-associated ascending aortopathy. J Thorac Cardiovasc Surg. 151(6):1718-1728 (2016).

Yoshizumi T, Zhu Y, Jiang H, D’Amore A, Sakaguchi H, Tchao J, Tobita K, Wagner WR. Timing effect of intramyocardial hydrogel injection for positively impacting left ventricular remodeling after myocardial infarction. Biomaterials. 83:182-93 (2016).

Pasta S, Phillippi JA, Tsamis A, D’Amore A, Raffa GM, Pilato M, Scardulla C, Watkins SC, Wagner WR, Gleason TG, Vorp DA. Constitutive modeling of ascending thoracic aortic aneurysms using microstructural parameters. Med Eng Phys. 38:121-30 (2016).

Uchida N, Sivaraman S, Amoroso NJ, Wagner WR, Nishiguchi A, Matsusaki M, Akashi M, Nagatomi J. Nanometer-sized extracellular matrix coating on polymer-based scaffold for tissue engineering applications. J Biomed Mater Res A. 104:94-103 (2016).

Fang J, Ye SH, Wang J, Zhao T, Mo X, Wagner WR. Thiol click modification of cyclic disulfide containing biodegradable polyurethane urea elastomers. Biomacromolecules. 16:1622-33 (2015).

Zhu Y, Jiang H, Ye SH, Yoshizumi T, Wagner WR. Tailoring the degradation rates of thermally responsive hydrogels designed for soft tissue injection by varying the autocatalytic potential. Biomaterials. 53:484–93 (2015).

Hemmasizadeh A, Tsamis A, Cheheltani R, Assari S, D’Amore A, Autieri M, Kiani MF, Pleshko N, Wagner WR, Watkins SC, Vorp D, Darvish K. Correlations between transmural mechanical and morphological properties in porcine thoracic descending aorta. J Mech Behav Biomed Mater. 47:12-20 (2015).

Hobson CM, Amoroso NJ, Amini R, Ungchusri E, Hong Y, D’Amore A, Sacks MS, Wagner WR. Fabrication of elastomeric scaffolds with curvilinear fibrous structures for heart valve leaflet engineering. J Biomed Mater Res A. 103:3101-6 (2015).

Ye SH, Arazawa DT, Zhu Y, Shankarraman V, Malkin AD, Kimmel JD, Gamble LJ, Ishihara K, Federspiel WJ, Wagner WR. Hollow fiber membrane modification with functional zwitterionic macromolecules for improved thromboresistance in artificial lungs. Langmuir. 31:2463-71 (2015).

Jamiolkowski MA, Woolley JR, Kameneva MV, Antaki JF, Wagner WR. Real time visualization and characterization of platelet deposition under flow onto clinically-relevant opaque surfaces. J Biomed Mater Res A. 103:1303-11 (2015).

Woolley JR, Kormos RL, Teuteberg JJ, Bermudez CA, Bhama JK, Lockard KL, Kunz NM, Wagner WR. Pre-operative liver dysfunction influences blood product administration and alterations in circulating hemostatic markers following ventricular assist device implantation. Eur J Cardiothorac Surg. 47:497-504 (2015).

Ye SH, Hong Y, Sakaguchi H, Shankarraman V, Luketich SK, D’Amore A, Wagner WR. Non-thrombogenic, biodegradable elastomeric polyurethanes with variable sulfobetaine content. ACS Appl Mater Interfaces. 6:22796-806 (2014).

Sanchez-Palencia DM, D’Amore A, Gonzalez-Mancera A, Wagner WR, Briceno JC. Effects of fabrication on the mechanics, microstructure and micromechanical environment of small intestinal submucosa scaffolds for vascular tissue engineering. J Biomech. 47:2766-2773 (2014).

Sakaguchi H, Amoroso NJ, Wagner WR. Engineering electrospun scaffolds to encourage cell infiltration. Engineered Cell Manipulation for Biomedical Applications (Nanomedicine and Nanotoxicology. M. Akashi, T. Akagi, M. Matsusaki, Eds. Springer Japan (2014).

Wu J, Funderburgh JL, Wagner WR. Biomaterials for refractive correction: corneal onlays and inlays. Science China Chemistry. 57:501-9 (2014).

Park DW, Ye SH, Jiang HB, Dutta D, Nonaka K, Wagner WR, Kim K. In vivo monitoring of structural and mechanical changes of tissue scaffolds by multi-modality imaging. Biomaterials. 35:7851-9 (2014).

D’Amore A, Amoroso NJ, Gottardi RL, Hobson C, Carruthers C, Watkins S, Wagner WR, Sacks M. From single fiber to macro-level mechanics: A structural finite-element model for elastomeric fibrous biomaterials. J Mech Behav Biomed Mater. 39:146-61 (2014).

Fu HL, Hong Y, Little SR, Wagner WR. Collagenase-labile polyurethane urea synthesis and processing into hollow fiber membranes. Biomacromolecules. 15:2924-32 (2014).

Jamiolkowski MA, Woolley JR, Kameneva MV, Antaki JF, Wagner WR. Real time visualization and characterization of platelet deposition under flow onto clinically-relevant opaque surfaces. J Biomed Mater Res A. 2015 Apr;103(4):1303-11. Epub 2014 May 6.

Fang J, Ye SH, Shankarraman V, Huang Y, Mo X, Wagner WR. Biodegradable poly(ester urethane)urea elastomers with variable amino content for subsequent functionalization with phosphorylcholine. Acta Biomater. 10:4639-49 (2014).

Task K, D’Amore A, Singh S, Candiello J, Jaramillo M, Wagner WR, Kumta P, Banerjee I. Systems level approach reveals the correlation of endoderm differentiation of mouse embryonic stem cells with specific microstructural cues of fibrin gels. J R Soc Interface. 11:20140009 (2014).

Shankarraman V, Kocyildirim E, Olia SE, Kameneva MV, Dzadony RJ, Maul TM, Simon MA, Champion HC, Wagner WR, Bermudez CA. Biocompatibility assessment of the Levitronix Centrimag adult ECMO circuit in a model of acute pulmonary hypertension. ASAIO J. 60:429–35 (2014).

Leng X, Wang J, Carson A, Chen X, Fu H, Ottoboni S, Wagner WR, Villanueva FS. Ultrasound detection of myocardial ischemic memory using an E-selectin targeting peptide amenable to human application. Mol Imaging. 13:1-9 (2014).

Koch RG, Tsamis A, D’Amore A, Wagner WR, Watkins SC, Gleason TG, Vorp DA. A custom image-based analysis tool for quantifying elastin and collagen micro-architecture in the wall of the human aorta from multi-photon microscopy. J Biomech. 47:935-43 (2014).

Takanari K, Hong Y, Hashizume R, Huber A, Amoroso N, D’Amore A, Badylak S, Wagner WR. Abdominal wall reconstruction by a regionally distinct biocomposite of extracellular matrix digest and a biodegradable elastomer. J Tissue Eng Regen Med. 2016 Sep;10(9):748-61. Epub 2013 Dec 27.

Perkins J, Hong Y, Ye SH, Wagner WR, Desai S. Direct writing of Bio-functional coatings for cardiovascular applications. J Biomed Mater Res A. 102:4290-300 (2014).

Wu J, Du Y, Mann MM, Funderburgh JL, Wagner WR. Corneal stromal stem cells versus corneal fibroblasts in generating structurally appropriate corneal stromal tissue. Exp Eye Res. 120C:71-81 (2014).

Nelson DM, Hashizume R, Yoshizumi T, Blakney AK, Ma Z, Wagner WR. Intramyocardial injection of a synthetic hydrogel with delivery of bFGF and IGF1 in a rat model of ischemic cardiomyopathy. Biomacromolecules. 15:1-11 (2014).

Woolley JR, Teuteberg JJ, Bermudez CA, Bhama JK, Lockard KL, Kormos RL, Wagner WR. Temporal leukocyte numbers and granulocyte activation in pulsatile and rotary ventricular assist device patients. Artif Organs. 38:447-55 (2014).

Tsamis A, Phillippi JA, Koch RG, Pasta S, D’Amore A, Watkins SC, Wagner WR, Gleason TG, Vorp DA. Fiber micro-architecture in the longitudinal-radial and circumferential-radial planes of ascending thoracic aortic aneurysm. J Biomech. 46:2787-94 (2013).

Remlinger NT, Gilbert TW, Yoshida M, Guest BN, Hashizume R, Weaver ML, Wagner WR, Brown BN, Tobita K, Wearden PD. Urinary bladder matrix promotes site appropriate tissue formation following right ventricle outflow tract repair. Organogenesis. 9:215-26 (2013).

Kimmel JD, Arazawa DT, Ye SH, Shankarraman V, Wagner WR, Federspiel WJ. Carbonic anhydrase immobilized on hollow fiber membranes using glutaraldehyde activated chitosan for artificial lung applications. J Mater Sci Mater Med. 24:2611-21 (2013).

Wu J, Du Y, Mann MM, Yang E, Funderburgh J, Wagner WR. Bioengineering organized, multi-lamellar human corneal stromal tissue by growth factor supplementation on highly aligned synthetic substrates. Tissue Eng Part A. 19:2063-75 (2013).

Yu J, Takanari K, Hong Y, Lee KW, Amoroso NJ, Wang Y, Wagner WR, Kim K. Non-invasive characterization of polyurethane-based tissue constructs in a rat abdominal repair model using high frequency ultrasound elasticity imaging. Biomaterials. 34:2701-9 (2013).

Hashizume R, Hong Y, Takanari K, Fujimoto KL, Tobita K, Wagner WR. The effect of polymer degradation time on functional outcomes of temporary elastic patch support in ischemic cardiomyopathy. Biomaterials. 34:7353-63 (2013).

Ambrosio F, Boninger ML, Brubaker CE, Delitto A, Wagner WR, Shields RK, Wolf SL, Rando TA. Guest Editorial: Emergent themes from Second Annual Symposium on Regenerative Rehabilitation, Pittsburgh, Pennsylvania. J Rehabil Res Dev. 50:vii-xiv (2013).

Ye SH, Jang YS, Yun YH, Shankarraman V, Woolley JR, Hong Y, Gamble LF, Ishihara K, Wagner WR. Surface modification of a biodegradable magnesium alloy with phosphorylcholine (PC) and sulfobetaine (SB) functional macromolecules for reduced thrombogenicity and acute corrosion resistance. Langmuir. 29:8320-7 (2013).

Fan R, Bayoumi AS, Chen P, Hobson CM, Wagner WR, Mayer, JE Jr, Sacks MS. Optimal elastomeric scaffold leaflet shape for pulmonary heart valve leaflet replacement. J Biomech. 46:662-9 (2013).

Hashizume R, Fujimoto KL, Hong Y, Guan J, Toma C, Tobita K, Wagner WR. Biodegradable elastic patch plasty ameliorates left ventricular adverse remodeling after ischemia–reperfusion injury: A preclinical study of a porous polyurethane material in a porcine model. J Thorac Cardiovasc Surg. 146:391-399 (2013).

Amoroso NJ, D’Amore A, Hong Y, Rivera CP, Sacks MS, Wagner WR. Microstructural manipulation of electrospun scaffolds for specific bending stiffness for heart valve tissue engineering. Acta Biomater. 8:4268-77 (2012).

Hong Y, Ye SH, Pelinescu AL, Wagner WR. Synthesis, characterization and paclitaxel release from a biodegradable, elastomeric, poly(ester urethane)urea bearing phosphorylcholine groups for reduced thrombogenicity. Biomacromolecules. 13:3686-94. (2012).

Fujimoto KL, Tobita K, Guan J, Hashizume R, Takanari K, Alfieri CM, Yutzey KE, Wagner WR. Placement of an elastic biodegradable cardiac patch on a subacute infarcted heart leads to cellularization with early developmental cardiomyocyte characteristics.  J Card Fail. 18:585-95 (2012).

Wu J, Du Y, Watkins SC, Funderburgh JL, Wagner WR. The engineering of organized human corneal tissue through the spatial guidance of corneal stromal stem cells. Biomaterials. 33:1343-52 (2012)

Deglau TE, Maul TM, Villanueva FS, Wagner WR. In vivo PEG-modification of vascular surfaces for targeted delivery. J Vasc Surg. 55:1087-95 (2012).

Nelson DM, Ma Z, Leeson CE, Wagner WR. Extended and sequential delivery of protein from injectable thermoresponsive hydrogels. J Biomed Mater Res, Part A. 100:776-85 (2012).

Hong Y, Takanari K, Amoroso NJ, Hashizume R, Brennan-Pierce EP, Freund JM, Badylak SF, Wagner WR. An elastomeric patch electrospun from a blended solution of dermal ECM and biodegradable polyurethane for rat abdominal wall repair. Tissue Eng Part C. 18:122-32 (2012).

Ma Z, Hong Y, Nelson DM, Pichamuthu JE, Leeson C, Wagner WR. Biodegradable polyurethane ureas with variable polyester or polycarbonate soft segments: effects of crystallinity, molecular weight and composition on mechanical properties. Biomacromolecules. 12:3265-74 (2011).

Hashizume R, Yamawaki-Ogata A, Ueda Y, Wagner WR, Narita Y. Mesenchymal stem cells attenuate angiotensin II-induced aortic aneurysm growth in apolipoprotein E-deficient mice. J Vasc Surg. 54:1743-52 (2011).

Johnson CA Jr, Shankarraman V, Wearden PD, Kocyildirim E, Maul TM, Marks JD, Richardson JS, Gellman BN, Borovetz HS, Dasse KA, Wagner WR. Platelet activation following implant of the Levitronix PediVAS in the ovine model. ASAIO J. 57:516-21 (2011).

He W, Nieponice A, Hong Y, Wagner WR, Vorp DA. Rapid engineered small diameter vascular grafts from smooth muscle cells. Cardiovascular Engineering and Technology. 2:149–59 (2011).

Stella JA, Liao J, Hong Y, Merryman WD, Wagner WR, Sacks MS. Tissue-to-cellular deformation coupling in cell-microintegrated elastomeric scaffolds. IUTAM proceedings of the Symposium on Cellular, Molecular and Tissue Mechanics, Springer, pp.81-89.

Hong Y, Huber A, Takanari K, Amoroso NJ, Hashizume R, Badylak SF, Wagner WR. Mechanical properties and in vivo behavior of a biodegradable synthetic polymer microfiber – extracellular matrix hydrogel biohybrid scaffold. Biomaterials. 32:3387-94 (2011).

Nelson DM, Baraniak PR, Ma Z, Guan J, Mason NS, Wagner WR. Controlled release of IGF-1 and HGF from a biodegradable polyurethane scaffold. Pharm Res. 28:1282-93 (2011).

Toma C, Fisher A, Wang J, Chen X, Grata M, Winston B, Leeman J, Kaya M, Fu H, Lavery L, Fischer D, Wagner WR, Villanueva FS. Vascular endoluminal delivery of stem cells using acoustic radiation force. Tissue Eng Part A. 17:1457-64 (2011).

Baraniak PR, Nelson DM, Leeson CE, Katakam AK, Friz JL, Cress DE, Hong Y, Guan J, Wagner WR. Spatial control of gene expression within a scaffold by localized inducer release. Biomaterials. 32:3062-71 (2011).

Amoroso NJ, D’Amore A, Hong Y, Wagner WR, Sacks MS. Elastomeric electrospun polyurethane scaffolds: the interrelationship between fabrication conditions, fiber topology, and mechanical properties. Advanced Materials. 23:106-111 (2011).

Fujimoto KL, Clause KC, Liu LJ, Tinney JP, Verma S, Wagner WR, Keller BB, Tobita K. Engineered fetal cardiac graft preserves its cardiomyocyte proliferation within postinfarcted myocardium and sustains cardiac function. Tissue Eng Part A. 17:585-96 (2011).

Soletti L, Nieponice A, Hong Y, Ye SH, Stankus JJ, Wagner WR, Vorp DA. In vivo performance of a phospholipid-coated bioerodable elastomeric graft for small-diameter vascular applications. J Biomed Mater Res A. 96:436-48 (2011).

Johnson CA Jr, Wearden PD, Kocyldirim E, Woolley JR, Maul TM, Ye SH, Strickler EM, Borovetz HS, Wagner WR. Platelet activation in ovines undergoing sham surgery or implant of the second generation PediaFlowTM pediatric ventricular assist device. Artificial Organs. 35:602-13 (2011).

Nelson DM, Ma Z, Fujimoto KL, Hashizume R, Wagner WR. Intra-myocardial biomaterial injection therapy in the treatment of heart failure: Materials, outcomes and challenges.  Acta Biomater. 7:1-15 (2011).

Johnson CA Jr, Vandenberghe S, Daly AR, Woolley JR, Snyder ST, Verkaik JE, Ye SH, Borovetz HS, Antaki JF, Wearden PD, Kameneva MV, Wagner WR. Biocompatibility assessment of the first generation PediaFlow™ pediatric ventricular assist device. Artificial Organs. 35:9-21 (2011).

Maul TM, Dudgeon DD, Beste MT, Hammer DA, Lazo JS, Villanueva FS, Wagner WR. Optimization of ultrasound contrast agents with computational models to improve selection of ligands and binding strength. Biotechnol Bioeng. 107:854-64 (2010).

He W, Nieponice A, Soletti L, Hong Y, Gharaibeh B, Crisan M, Usas A, Peault B, Huard J, Wagner WR, Vorp DA. Pericyte-based human tissue engineered vascular grafts. Biomaterials. 31:8235-44 (2010).

Chapman MP, Lopez Gonzalez JL, Goyette BE, Fujimoto KL, Ma Z, Wagner WR, Zenati MA, Riviere CN. Application of the HeartLander crawling robot for injection of a thermally sensitive anti-remodeling agent for myocardial infarction therapy. Conf Proc IEEE Eng Med Biol Soc. 1:5428-31 (2010).

Wagner WR, Griffith BP. Reconstructing the lung. Science. 329:520-2 (2010).

Ma Z, Nelson DM, Hong Y, Wagner WR. A thermally responsive injectable hydrogel incorporating methacrylate-polylactide for hydrolytic lability. Biomacromolecules. 11:1873-81 (2010).

Ye SH, Johnson CA Jr, Woolley JR, Murata H, Gamble LJ, Ishihara K, Wagner WR. Simple surface modification of a titanium alloy with silanated zwitterionic phosphorylcholine or sulfobetaine modifiers to reduce thrombogenicity. Colloids and Surfaces B: Biointerfaces. 79:357-64 (2010).

D’Amore A. Stella JA, Wagner WR, Sacks MS. Characterization of the complete fiber network topology of planar fibrous tissues and scaffolds. Biomaterials. 31:5345-54 (2010).

Hong Y, Guan J, Fujimoto KL, Hashizume R, Pelinescu AL, Wagner WR. Tailoring the degradation kinetics of poly(ester-carbonateurethane) urea thermoplastic elastomers for tissue engineering scaffolds. Biomaterials. 31:4249–58 (2010).

Hashizume R, Fujimoto KL, Hong Y, Amoroso NJ, Tobita K, Miki T, Keller BB, Sacks MS, Wagner WR. Morphological and mechanical characteristics of the reconstructed rat abdominal wall following use of a wet electrospun biodegradable polyurethane elastomer scaffold. Biomaterials. 31:3253-65 (2010).

Polk AA, Maul TM, McKeel DT, Snyder TA, Lehocky CA, Pitt B, Stolz DB, Federspiel WJ, Wagner WR. A biohybrid artificial lung prototype with active mixing of endothelialized microporous hollow fibers. Biotechnol Bioeng. 106:490-500 (2010).

Wang F, Li Z, Khan M, Tamama K, Kuppusamy P, Wagner WR, Sen CK, Guan J. Injectable, rapid gelling and highly flexible hydrogel composites as growth factor and cell carriers. Acta Biomaterialia. 6:1978-91 (2010).

Nieponice A, Soletti L, Guan J, Hong Y, Gharaibeh B, Maul TM, Huard J, Wagner WR, Vorp DA. In-vivo assessment of a tissue-engineered vascular graft combining a biodegradable elastomeric scaffold and muscle-derived stem cells in a rat model. Tissue Engineering Part A. 16:1215-23 (2010).

Clause KC, Tinney JP, Liu JL, Gharaibeh B, Huard J, Kirk J, Shroff SG, Fujimoto KL, Wagner WR, Ralphe JC, Keller BB, Tobita K. A three-dimensional gel bioreactor for assessment of cardiomyocyte induction in skeletal muscle-derived stem cells. Tissue Engineering Part C. 16:375-85 (2010).

Stella JA, D’Amore A, Wagner WR, Sacks MS. On the biomechanical function of scaffolds for engineering load bearing soft tissues. Acta Biomaterialia. 6:2365-81 (2010).

Soletti L, Hong Y, Guan J, Stankus JJ, El-Kurdi MS, Wagner WR, Vorp DA. A bi-layered elastomeric scaffold for tissue engineering of small-diameter vascular grafts. Acta Biomaterialia. 6:110-22 (2010).

Oh HI, Ye SH, Johnson CA Jr., Woolley JR, Federspiel WJ, Wagner WR. Hemocompatibility assessment of carbonic anhydrase modified hollow fiber membranes for artificial lungs. Artificial Organs. 34:439-42 (2010).

Stella JA, Wagner WR, Sacks MS. Scale dependent fiber kinematics of elastomeric electrospun scaffolds for soft tissue engineering. J Biomed Mater Res A. 93:1032-42 (2010).

Soletti L, Hong Y, Guan J, Stankus JJ, El-Kurdi MS, Wagner WR, Vorp DA. A bi-layered elastomeric scaffold for tissue engineering of small-diameter vascular grafts. Acta Biomaterialia. 6:110-22 (2010).

Oh HI, Ye SH, Johnson CA Jr., Woolley JR, Federspiel WJ, Wagner WR. Hemocompatibility assessment of carbonic anhydrase modified hollow fiber membranes for artificial lungs. Artificial Organs. 34:439-42 (2010).

Stella JA, Wagner WR, Sacks MS. Scale dependent fiber kinematics of elastomeric electrospun scaffolds for soft tissue engineering. J Biomed Mater Res A. 93:1032-42 (2010).

Ye SH, Johnson CA Jr., Woolley JR, Oh HI, Gamble LJ, Ishihara K, Wagner WR. Surface modification of a titanium alloy with a phospholipid polymer prepared by a plasma-induced grafting technique to improve surface thromboresistance. Colloids and Surfaces B: Biointerfaces. 74:96–102 (2009).

Fujimoto KL, Ma Z, Nelson DM, Hashizume R, Guan J, Tobita K, Wagner WR. Synthesis, characterization and therapeutic efficacy of a biodegradable, thermoresponsive hydrogel designed for application in chronic infarcted myocardium. Biomaterials. 30:4357-68 (2009).

Wang F, Li Z, Lannutti JL, Wagner WR, Guan J. Synthesis, characterization and surface modification of low moduli poly(ether carbonate urethane)ureas for soft tissue engineering. Acta Biomaterialia. 5:2901-12 (2009).

Fujimoto KL, Miki T, Liu LJ, Hashizume R, Strom SC, Wagner WR, Keller BB, Tobita K. Naïve rat amnion-derived cell transplantation improved left ventricular function and reduced myocardial scar of post-infarcted heart. Cell Transplant. 18:477-486 (2009).

Hong Y, Ye SH, Nieponice A, Soletti L, Vorp DA, Wagner WR. A small diameter, fibrous vascular conduit generated from a poly(ester urethane)urea and phospholipid polymer blend. Biomaterials. 30:2457–67 (2009).

Toma C, Wagner WR, Bowry S, Schwartz A, Villanueva F. Fate of culture-expanded mesenchymal stem cells in the microvasculature: In vivo observations of cell kinetics. Circ Res. 104:398–402 (2009).

Ye SH, Johnson CA Jr., Woolley JR, Snyder TA, Gamble LJ, Wagner WR. Covalent surface modification of a titanium alloy with a phosphorylcholine-containing copolymer for reduced thrombogenicity in cardiovascular devices. J Biomed Mater Res A. 91:18-28 (2009).

Burgess KA, Hu HH, Wagner WR, Federspiel WJ. Towards microfabricated biohybrid artificial lung modules for chronic respiratory support. Biomed Microdev. 11:117–27 (2009).

Guan J, Fujimoto KL, Wagner WR. Elastase-sensitive elastomeric scaffolds with variable anisotropy for soft tissue engineering. Pharm Res. 25:2400–2412 (2008).

El-Kurdi MS, Hong Y, Stankus JJ, Soletti L, Wagner WR, Vorp DA. Transient elastic support for vein grafts using a constricting microfibrillar polymer wrap. Biomaterials. 29:3213-3220 (2008).

Stella JA, Liao J, Hong Y, Merryman WD, Wagner WR, Sacks MS. Tissue-to-cellular level deformation coupling in cell microintegrated elastomeric scaffolds. Biomaterials. 29:3228-3236 (2008).

Guan J, Hong Y, Ma Z, Wagner WR. Protein-reactive, thermoresponsive copolymers with high flexibility and biodegradability. Biomacromolecules. 9:1283-1292 (2008).

Simon MA, Watson J, Baldwin JT, Wagner WR, Borovetz HS. Current and future considerations in the use of mechanical circulatory support devices. Annu Rev Biomed Eng. 10:59-84 (2008).

Hong Y, Fujimoto K, Hashizume R, Guan J, Stankus JJ, Tobita K, Wagner WR. Generating elastic, biodegradable polyurethane/poly(lactide-co-glycolide) fibrous sheets with controlled antibiotic release via two-stream electrospinning. Biomacromolecules. 9:1200-1207 (2008).

Stankus JJ, Freytes DO, Badylak SF, Wagner WR. Hybrid nanofibrous scaffolds from electrospinning of a synthetic biodegradable elastomer and urinary bladder matrix. J Biomater Sci Polym Ed. 19:635–652 (2008).

Villanueva FS, Wagner WR. Ultrasound molecular imaging of cardiovascular disease. Nat Clin Pract Cardiovasc Med. 5:S26-32 (2008).

Johnson CA Jr., Snyder TA, Woolley JR, Wagner WR. Flow cytometric assays for quantifying activated ovine platelets. Artif Organs. 32:136–145 (2008).

Nieponice A, Soletti L, MS, Guan J, PhD, Deasy BM, Huard J, Wagner WR, Vorp DA. Development of a tissue engineered vascular graft combining a biodegradable scaffold, muscle-derived stem cells and a rotational vacuum seeding technique. Biomaterials. 29:825-833 (2008).

Dasse KA, Gellman BN, Kameneva MV, Woolley J, Johnson C, Gempp T, Marks JD, Kent S, Koert A, Richardson JS, Franklin S, Snyder TA, Wearden P, Wagner WR, Gilbert RJ, Borovetz HS. Assessment of hydraulic performance and biocompatibility of a MagLev centrifugal pump system designed for pediatric cardiac or cardiopulmonary support. ASAIO J. 53:771-777 (2007).

Guan J, Stankus JJ, Wagner WR. Biodegradable elastomeric scaffolds with basic fibroblast growth factor release. J Control Release. 120:70-78 (2007).

Fujimoto KL, Tobita K, Merryman WD, Guan, J, Momoi N, Stolz DB, Sacks MS, Keller BB, Wagner WR. An elastic, biodegradable cardiac patch induces contractile smooth muscle and improves cardiac remodeling and function in sub-acute myocardial infarction. J Am Coll Cardiol. 49:2292-2300 (2007).

Stankus JJ, Soletti L, Fujimoto K, Hong Y, Vorp DA, Wagner WR. Fabrication of cell microintegrated blood vessel constructs through electrohydrodynamic atomization. Biomaterials. 28:2738–2746 (2007).

Villanueva FS, Lu E, Bowry S, Kilic S, Tom E, Wang J, Gretton J, Pacella JJ, Wagner WR. Myocardial ischemic memory imaging using molecular echocardiography. Circulation. 115:345-352 (2007).

Deglau TE, Johnson JD, Villanueva FS, Wagner WR. Targeting microspheres and cells to PEG-modified biological surfaces. J Biomed Mater Res A. 81:578–585 (2007).

Snyder TA, Litwak KN, Tsukui H, Akimoto T, Kihara S, Yamazaki K, Wagner WR. Leukocyte-platelet aggregates and monocyte tissue factor expression in bovines implanted with ventricular assist devices. Artif Organs. 31:126-131(2007).

Fujimoto KL, Guan J, Oshima H, Sakai T, Wagner WR. In vivo evaluation of a porous, elastic, biodegradable patch for reconstructive cardiac procedures. Ann Thorac Surg. 83:648-654 (2007).

Snyder TA, Tsukui H, Kihara S, Akimoto T, Litwak KN, Kameneva MV, Yamazaki K, Wagner WR. Preclinical biocompatibility assessment of the EVAHEART ventricular assist device: coating comparison and platelet activation. J Biomed Mater Res A. 81:85-92 (2007).

Soletti L, Nieponice A, Guan J, Stankus JJ, Wagner WR, Vorp DA. A seeding device for tissue engineered tubular structures. Biomaterials. 27:4863-4870 (2006).

Guan J, Stankus JJ, Wagner WR. Soft tissue scaffolds. Encyclopedia of Biomedical Engineering. G. Pins, Ed., J. Wiley and Sons (2006).

Snyder TA, Eash HJ, Litwak KN, Frankowski BJ, Hattler BG, Federspiel WJ, Wagner WR. Blood biocompatibility assessment of an intravenous gas exchange device. Artif Organs. 30:657–664 (2006).

Guan J, Stankus JJ, Wagner WR. Development of composite porous scaffolds based on collagen and biodegradable poly(ester urethane)urea. Cell Transplant. 15(S1):17-27 (2006).

Courtney T, Sacks MS, Stankus J, Guan J, Wagner WR. Design and Analysis of tissue engineered scaffolds that mimic soft tissue mechanical anisotropy. Biomaterials. 27:3631- 3638 (2006).

Ramaswami P, Wagner WR. Cardiovascular tissue engineering. An Introduction to Biomaterials. S.A. Guelcher and J.O. Hollinger, Eds., CRC Press, Boca Raton, FL, (2006).

Borovetz HS, Badylak S, Boston JR, Johnson C, Kormos R, Kameneva MV, Simaan M, Snyder TA, Tsukui H, Wagner WR, Woolley J, Antaki J, Diao C, Vandenberghe S, Keller B,  Morell V, Wearden P, Webber S, Gardiner J, Li CM, Paden D, Paden B, Snyder S, Wu J, Bearnson G, Hawkins JA, Jacobs G, Kirk J, Khanwilkar P, Kouretas PC, Long J, Shaddy RE. Towards the development of a pediatric ventricular assist device. Cell Transplant. 15(S1):69-74 (2006).

Xu H, Kaar JL, Russell AJ, Wagner WR. Characterizing the modification of surface proteins with poly(ethylene glycol) to interrupt platelet adhesion. Biomaterials. 27:3125– 3135 (2006).

Stankus JJ, Guan J, Fujimoto K, Wagner WR. Microintegrating smooth muscle cells into a biodegradable, elastomeric fiber matrix. Biomaterials. 27:735–744 (2006).

Wearden PD, Morell VO, Keller BB, Webber SA, Borovetz HS, Badylak SF, Boston JR, Kormos RL, Kameneva MV, Simaan M, Snyder TA, Tsukui H, Wagner WR, Antaki JF, Diao C, Vandenberghe S, Gardiner J, Li CM, Noh D, Paden D, Paden B, Wu J, Bearnson GB, Jacobs G, Kirk J, Khanwilkar P, Long JW, Miles S, Hawkins JA, Kouretas PC, Shaddy RE. The PediaFlow pediatric ventricular assist device. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 9:92-98 (2006).

Weller GER, Villanueva FS, Tom E, Wagner WR. Targeted ultrasound contrast agents: In vitro assessment of endothelial dysfunction and multi-targeting to ICAM-1 and sialyl Lewisx. Biotechnol Bioeng. 92:780-788 (2005).

Wu J, Antaki JF, Wagner WR, Snyder TA, Paden BE, Borovetz HS. Elimination of adverse leakage flow in a miniature pediatric centrifugal blood pump by computational fluid dynamics-based design optimization. ASAIO J. 51:636–643 (2005).

Guan J, Wagner WR. Synthesis, characterization and cytocompatibility of polyurethane urea elastomers with designed elastase sensitivity. Biomacromolecules. 6:2833-2842 (2005).

Wu J, Antaki JF, Snyder TA, Wagner WR, Borovetz HS, Paden BE. Design optimization of blood shearing instrument by computational fluid dynamics. Artif Organs. 29:482-489 (2005).

Weller GER, Wong MKK, Modzelewski RA, Lu E, Klibanov AL, Wagner WR, Villanueva FS. Ultrasonic imaging of tumor angiogenesis using contrast microbubbles targeted via the tumor-binding peptide arginine-arginine-leucine. Cancer Res. 65:533-539 (2005).

Guan J, Fujimoto KL, Sacks MS, Wagner WR. Preparation and characterization of highly porous, biodegradable polyurethane scaffolds for soft tissue applications. Biomaterials. 26:3961-71 (2005).

Stankus JJ, Guan J, Wagner WR. Fabrication of biodegradable, elastomeric scaffolds with sub-micron morphologies. J Biomed Mater Res. 70A:603-14 (2004).

Stankus JJ, Guan J, Wagner WR. Elastomers, biodegradable. Encyclopedia of Biomaterials and Biomedical Engineering. G.E. Wnek and G.L. Bowlin, Eds., Marcel Dekker, NY, (2004).

Villanueva FS, Wagner WR, Vannan MA, Narula J. Targeted ultrasound imaging using microbubbles. Cardiol Clin. 22:283-98 (2004).

Wagner WR, Borovetz HS, Griffith BP. Implantable cardiac assist devices. Biomaterials Science: An Introduction to Materials in Medicine, 2nd Edition. Academic Press, San Diego, CA, (2004).

Guan J, Sacks MS, Beckman EJ, Wagner WR. Biodegradable poly(ether ester urethane)urea elastomers based on poly(ether ester) triblock copolymers and putrescine: synthesis, characterization and cytocompatibility. Biomaterials. 25:85-96 (2004).

Weller GER, Lu E, Csikari MM, Klibanov AL, Fischer D, Wagner WR, Villanueva FS. Ultrasound imaging of acute cardiac transplant rejection with microbubbles targeted to intercellular adhesion molecule-1. Circulation. 108:218-24 (2003).

Eash HJ, Frankowski BJ, Litwak K, Wagner WR, Hattler BG, Federspiel WJ. Acute in-vivo testing of a respiratory assist catheter: Implants in calves versus sheep. ASAIO J. 49:370-377 (2003).

Gage KL, Wagner WR. Cardiovascular Devices. Standard Handbook of Biomedical Engineering and Design, McGraw-Hill, New York 20.1-20.48, (2003).

Lu E, Wagner WR, Schellenberger U, Abraham JA, Klibanov AL, Woulfe SR, Csikari MM, Fischer D, Schreiner GF, Brandenburger GH, Villanueva FS. Targeted in vivo labeling of receptors for vascular endothelial growth factor: Approach to identification of ischemic tissue. Circulation. 108:97-103 (2003).

Weller GER, Villanueva FS, Klibanov AL, Wagner WR. Modulating targeted adhesion of an ultrasound contrast agent to dysfunctional endothelium. Ann Biomed Eng. 30:1012– 1019 (2002).

Gage KL, Gartner MJ, Burgreen GW, Wagner WR. Predicting membrane oxygenator pressure drop using computational fluid dynamics. Artif Organs. 26:600-607 (2002).

Snyder TA, Watach MJ, Litwak KN, Wagner WR. Platelet activation, aggregation, and life span in calves implanted with axial flow ventricular assist devices. Ann Thorac Surg. 73:1933-1938 (2002).

Villanueva FS, Klibanov A, Wagner WR. Microbubble-endothelial cell interactions as a basis for assessing endothelial function. Echocardiography. 19:427-438 (2002).

Guan J, Sacks MS, Beckman EJ, Wagner WR. Synthesis, characterization and cytocompatibility of elastomeric, biodegradable poly(ester-urethane) ureas based on poly(caprolactone) and putrescine. J Biomed Mater Res. 61:493-503 (2002).

Burchenal JEB, Deible CR, Deglau TE, Russell AJ, Beckman EJ, Wagner WR. Polyethylene glycol diisocyanate decreases platelet deposition after balloon injury of rabbit femoral arteries. J Thromb Thrombolysis. 13:27-33 (2002).

Whyte EM, Pollock BG, Wagner WR, Mulsant BH, Ferrell RE, Mazumdar S, Reynolds CF III. Influence of serotonin-transporter-linked promoter region polymorphism on platelet activation in geriatric depression. Am J Psychiatry. 158:2074-2076 (2001).

Villanueva FS, Wagner WR, Klibanov, AL. Targeted ultrasound contrast agents: identification of endothelial dysfunction. Ultrasound Contrast Agents: Basic Principles and Clinical Applications, 2nd Edition. Martin Dunitz Publishers, London, 353-365, (2001).

Wagner WR, Schaub RD, Sorensen EN, Snyder TA, Wilhelm CR, Winowich S, Borovetz HS, Kormos RL. Blood biocompatibility analysis in the setting of ventricular assist devices. J Biomater Sci Polym Ed. 11:1239-1259 (2000).

Wagner WR, Gage KL. Thrombosis and thromboembolism in stent grafts: evaluating Virchow’s triad. Stent Graft Update. Medical and Engineering Publishers. Washington, DC, 125-140, (2000).

Panza JL, Wagner WR, Rilo HLR, Rao RH, Beckman EJ, Russell AJ. Treatment of rat pancreatic islets with reactive PEG. Biomaterials. 21:1155-1164 (2000).

Heesch CM, Wilhelm CR, Ristich J, Adnane J, Bontempo FA, Wagner WR. Cocaine activates platelets and increases the formation of circulating platelet containing microaggregates in humans. Heart. 83:688-695 (2000).

Pollock BG, Laghrissi-Thode F, Wagner WR. Evaluation of platelet activation in depressed patients with ischemic heart disease after paroxetine or nortriptyline treatment. J Clin Psychopharmacol. 20:137-140 (2000).

Gartner MJ, Wilhelm CR, Gage KL, Pham SM, Fabrizio C, Wagner WR. Modeling flow effects on thrombotic deposition in a membrane oxygenator. Artif Organs. 24:29-36 (2000).

Schaub RD, Kameneva MV, Borovetz HS, Wagner WR. Assessing acute platelet adhesion on opaque metallic and polymeric biomaterials with fiber optic microscopy. J Biomed Mater Res. 49:460-468 (2000).

Wilhelm CR, Ristich J, Knepper LE, Holubkov R, Wisniewski SR, Kormos RL, Wagner WR. Measurement of hemostatic indices in conjunction with transcranial Doppler sonography in ventricular assist device patients. Stroke. 30:2554-2561 (1999).

Klibanov AL, Hughes MS, Villanueva FS, Jankowski RJ, Wagner WR, Wojdyla JK, Wible JH, Brandenburger GH. Targeting and ultrasound imaging of microbubble-based contrast agents. Magnetic Resonance Materials in Physics, Biology and Medicine(MAGMA). 8:177-184 (1999).

Orban JM, Chapman TM, Wagner WR, Jankowski R. Easily grafted polyurethanes with reactive main chain functional groups. Synthesis, characterization, and antithrombogenicity of poly(ethylene glycol)-grafted poly(urethanes). Journal of Polymer Science: Part A: Polymer Chemistry. 37:3441-3448 (1999).

Jankowski RJ, Wagner WR. Directions in cardiovascular tissue engineering. Clin Plast Surg. 26:605-616, (1999).

Sorensen EN, Burgreen GW, Wagner WR, Antaki JF. Computational simulation of platelet deposition and activation: II. Results for Poiseuille flow over collagen. Ann Biomed Eng. 27:449-458 (1999).

Sorensen EN, Burgreen GW, Wagner WR, Antaki JF. Computational simulation of platelet deposition and activation: I. Model development and properties. Ann Biomed Eng. 27:436-448 (1999).

Deible CR, Petrosko P, Johnson PC, Beckman EJ, Russell AJ, Wagner WR. Molecular barriers to biomaterial thrombosis by modification of surface proteins with polyethylene glycol. Biomaterials. 19:1885-1893 (1998

Baker LC, Kameneva MV, Watach MJ, Litwak P, Wagner WR. Assessment of bovine platelet life span with biotinylation and flow cytometry. Artif Organs. 22:799-803 (1998).

Villanueva FS, Jankowski RJ, Klibanov S, Pina ML, Alber S, Watkins SC, Wagner WR. Microbubbles targeted to intercellular adhesion molecule-1 bind to activated coronary artery endothelial cells. Circulation. 98:1-5 (1998).

Baker LC, Davis WC, Autieri J, Watach M, Yamazaki K, Litwak P, Wagner WR. Flow cytometric assays to detect platelet activation and aggregation in device-implanted calves. J Biomed Mater Res.41:312-321 (1998).

Wilhelm CR, Ristich J, Kormos RL, Wagner WR. Monocyte tissue factor expression and ongoing complement generation in ventricular assist device patients. Ann Thorac Surg. 65:1071-1076 (1998).

Deible CR, Beckman EJ, Russell AJ, Wagner WR. Creating molecular barriers to acute platelet deposition on damaged arteries with reactive polyethylene glycol. J Biomed Mater Res. 41:251-256 (1998).

Jankowski RJ, Severyn DA, Vorp DA, Wagner WR. The effect of retroviral transduction on human endothelial cell phenotype and adhesion to Dacron vascular grafts. J Vasc Surg. 26:676-684 (1997).

Wagner WR, Muzzio D, Rilo HR, Deglau T, Ataai MM, Michalopolous G, Block GD. Effect of growth factors and defined medium on primary hepatocyte culture on polyester carriers with varying surface treatment. Tissue Eng. 3:289-301 (1997).

Villanueva FS, Jankowski RJ, Manaugh C, Wagner WR. Albumin microbubble adherence to human coronary endothelium: implications for assessment of endothelial function using myocardial contrast echocardiography. J Am Coll Cardiol. 30:689-693 (1997).

Laghrissi-Thode F, Wagner WR, Pollock BG, Johnson PC, Finkel MS. Elevated platelet factor 4 and β-thromboglobulin plasma levels in depressed patients with ischemic heart disease. Biol Psychiatry. 42:290-295 (1997).

Wagner WR, Pachence JM, Ristich J, Johnson PC. Comparative in vitro analysis of topical hemostatic agents. J Surg Res.66:100-108 (1996).

Yamazaki K, Kameneva M, Wagner W, Antaki J, Tatka J, Kerrigan J, Tomczak J, Yang Z, Konishi H, Borovetz H, Griffith B, Koyanagi H, Kormos R. Bearing seizure in a rotational blood pump: mechanism and potential solutions. Artificial Heart 5: Heart Replacement. Springer-Verlag, New York, 371-376 (1996).

Andreopoulos FM, Deible CR, Stauffer MT, Weber S, Wagner WR, Beckman EJ, Russell AJ. Photoreversible hydrogel synthesis via photopolymerization of PEG-based polymers. J Am Chem Soc. 118:6235-6240 (1996).

Wagner WR, Johnson PC. Therapeutic techniques for reducing thrombosis following cardiovascular implants. Probl Gen Surg. 11:241-264, (1994).

Wagner WR, Johnson PC, Thompson KA, Marrone GC. Heparin-coated cardiopulmonary bypass circuits: hemostatic alterations and postoperative blood loss. Ann Thorac Surg. 58:734-741 (1994).

Eidelman BH, Obrist WD, Wagner WR, Kormos R, Griffith B. Cerebrovascular complications associated with the use of artificial circulatory support services. Neurol Clin. 11:463-474 (1993).

Wagner WR, Johnson PC, Kormos RL, Griffith BP. Evaluation of bioprosthetic valve-associated thrombus in ventricular assist device patients. Circulation. 88:2023-2029 (1993).

Wagner WR, Hubbell JA. Evidence for a role in thrombus stabilization for thromboxane A2 in human platelet deposition on collagen. J Lab Clin Med. 119:690-697 (1992).

Wagner WR, Hubbell JA. ADP receptor antagonists and converting enzyme systems reduce platelet deposition onto collagen. Thromb Haemost. 67:461-467 (1992).

Hubbell JA, Pohl PI, Wagner WR. The use of laser-light scattering and controlled shear in platelet aggregometry. Thromb Haemost. 65:601-607 (1991).

Wagner WR, Hubbell JA. Local thrombin synthesis and fibrin formation in an in-vitro thrombosis model result in platelet recruitment and thrombus stabilization on collagen in heparinized blood. J Lab Clin Med. 116:636-650 (1990).