An international group of scientists in the joint study of the laboratory of the Wistar Institute, University of Pittsburgh, and I.M. Sechenov First Moscow State Medical University discovered the change in activity of one of the immune cells types called neutrophils during cancer development: They begin to prevent other immune cells from fighting tumors, and thus decelerate treatment. The scientists found protein causing such changes and demonstrated that suppressing its activity in the cells delays cancer development. The research details are published in Nature. McGowan Institute for Regenerative Medicine affiliated faculty member Valerian Kagan, PhD, Professor and Vice-Chairman in the Department of Environmental and Occupational Health as well as a Professor in the Department of Pharmacology and Chemical Biology, the Department of Radiation Oncology, and the Department of Chemistry at the University of Pittsburgh, and also the Director of the Center for Free Radical and Antioxidant Health, is a co-author of the study.
