The Department of Chemical and Petroleum Engineering Spring Term 2020 Outstanding PhD Paper winner is Michelle Pressly, BS, a PhD candidate in the laboratory of McGowan Institute for Regenerative Medicine affiliated faculty member Robert Parker, PhD, Professor in the Department of Chemical and Petroleum Engineering at the University of Pittsburgh. She published the journal manuscript titled “Accelerating availability of clinically-relevant parameter estimates from thromboelastogram point-of-care device” in the Journal of Trauma and Acute Care Surgery. McGowan Institute affiliated faculty member Gilles Clermont, MD, Professor of Critical Care Medicine, of Industrial Engineering, and of Mathematics at the University of Pittsburgh, is also a co-author of this publication.
The goal of the work was to predict coagulopathy, which affects 1 in 3 trauma patients. Current test results for these patients can take over an hour to report. Ms. Pressly found that using only the first 3 minutes of data, the team’s algorithm could predict test results with high accuracy (with an area under the receiver operating characteristic curve of 0.95). She took this a step further by using the first 4 and 5 minutes to predict platelet and packed red blood cell transfusion needs, respectively. This work provides actionable results over 50 minutes sooner than was previously possible.
Congratulations, Ms. Pressly!
Illustration: ResearchGate (Pressly) and McGowan Institute (Parker/Clermont).
Paper (Accelerating availability of clinically-relevant parameter estimates from thromboelastogram point-of-care device. Michelle A. Pressly, BS, Robert S. Parker, PhD, Matthew D. Neal, MD, Jason L. Sperry, MD, and Gilles Clermont, MD. Journal of Trauma and Acute Care Surgery, Volume 88, Number 5, Pages 654-660.)