Mo R. Ebrahimkhani, MD

Dr. Mo Ebrahimkhani is an Associate Professor in the Department of Pathology, School of Medicine, University of Pittsburgh.  He is also a member of the Division of Experimental Pathology and the Pittsburgh Liver Research Center. Prior to his current position he was an assistant professor in the School of Biological and Health Systems Engineering at Arizona State University and adjunct faculty of medicine at Mayo Clinic. He performed his Postdoctoral training at the Department of Biological Engineering in Massachusetts Institute of Technology (MIT).

Dr. Ebrahimkhani has an MD degree from Tehran University of Medical Sciences and was awarded a European Association for Study of Liver Sheila Sherlock Fellowship to investigate regenerative processes at University College London.  His lab combines human stem cells, synthetic biology and in vivo mouse models to understand tissue development and regeneration and develop technologies to modulate these processes in a personalized fashion. Dr. Ebrahimkhani is the recipient of several research awards including RO1s from NIH, Mayo Clinic accelerated regenerative medicine award and New Investigator Award from Arizona Biomedical Research Council. He is also a member of PLOS ONE Editorial Board (2018- present).

He directs THE LABORATORY FOR SYNTHETIC BIOLOGY AND REGENERATIVE MEDICINE. His lab research combines systems and synthetic biology-based approaches to program development of induced pluripotent stem cells across the developmental trajectories and towards human designer liver organoids and hematopoietic niches. This approach will open novel opportunities for next generation genomically engineered human tissues, personalized disease modeling and more effective regenerative therapies. His vision is to advance regenerative medicine through integrating systems and synthetic biology.

Dr. Ebrahimkhani’s lab research interests include:

  1. Human Based Multicellular Systems (i.e. Liver organoids)
  2. Synthetic Biology and Stem Cell Bioengineering (i.e. Synthetic Morphogenesis)
  3. Genetic Engineering (i.e. Gene circuits for programming cell fates and epigenetic states)
  4. Early Developmental Modeling
  5. Regeneration and Repair

View a list of Dr. Ebrahimkhani’s publications here.