Authors: Zheng B, Caro B, Crisan M, Sun B Li G, Logar A, Yap S, Pollett JB, Drowley L, Cassino T, Gharaibeh B, Deasy BM, Huard J, Peault B
Title: Prospective identification of myogenic endothelial cells in human skeletal muscle.
Summary: Myoendothelial cells taken from the blood vessels are much more efficient at forming muscle than other sources of stem cells known as satellite and endothelial cells. A thousand myoendothelial cells transplanted into the injured skeletal muscle of immunodeficient mice produced, on average, 89 muscle fibers, compared with nine and five muscle fibers for endothelial and satellite cells, respectively. Myoendothelial cells also showed no propensity to form tumors, a concern with other stem cell therapies.
Source: Nature Biotechnology. 2007 Sep;25(9): 1025-34