• Pitt
  • Health Sciences
  • UPMC
Regenerative Medicine at the McGowan InstituteRegenerative Medicine at the McGowan InstituteRegenerative Medicine at the McGowan InstituteRegenerative Medicine at the McGowan Institute
  • Home
  • Our People
    • Faculty/Staff Bios
    • Core Faculty Publications
    • Administrative Resources
  • Our Technologies
  • About Us
    • Welcome
    • Video
    • Mission Statement
    • What Is Regenerative Medicine?
    • Executive Committee
    • Contact Us
    • Clinical Site
  • Our Research
    • Focus Areas
      • Tissue Engineering and Biomaterials
      • Cellular Therapies
      • Medical Devices and Artificial Organs
      • Clinical Translation
    • Matrix
    • Centers
    • Laboratories
    • Clinical Trials
    • Initiatives
  • Media
    • Current News
    • News Archive
    • Video
    • Podcasts
    • Newsletter
    • Grant of the Month
    • Publication of the Month
    • Media Contact
    • Video Links
  • Professional Development
    • Seminar Series
    • Special Events
    • Student Interest Groups
    • CATER
    • Post-Doctoral Opportunities
    • Career Opportunities
    • Wiegand Summer Internship
    • Admissions
    • Summer School
    • 2022 Scientific Retreat

Publication of the Month

  • Podcasts
  • News Archive
    • Cellular Therapy
  • Current News
  • Media Contact
  • Newsletter
  • Grant of the Month
  • Publication of the Month
  • Categories
  • Video Links
Home Media Publication of the MonthPage 17

Publication of the Month | May 2006

By The McGowan Institute For Regenerative Medicine | Publication of the Month 2006, Publication of the Month | 0 comment | 30 July, 2015 | 0
Author(s): Todd Courtney, Michael S. Sacks, John Stankus, Jianjun Guan, William R. Wagner

Title: Design and analysis of tissue engineering scaffolds that mimic soft tissue mechanical anisotropy Read More

Publication of the Month | April 2006

By The McGowan Institute For Regenerative Medicine | Publication of the Month 2006, Publication of the Month | 0 comment | 30 July, 2015 | 0
Author(s): Tavian, Manuela (a); Zheng, Bo (b); Oberlin, Estelle (a); Crisan, Mihaela (c); Sun, Bin (c); Huard, Johnny (b); Peault, Bruno (a,c)

a) Inserm U506, Hopital Paul Brousse, Villejuif, France

b) Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA Read More

Publication of the Month | March 2006

By The McGowan Institute For Regenerative Medicine | Publication of the Month 2006, Publication of the Month | 0 comment | 30 July, 2015 | 0
Author(s): Srikanth Ranganathan (1), Eric Williams (2), Philip Ganchev (2), Vanathi Gopalakrishnan (2), David Lacomis (3), Leo Urbinelli (4), Kristyn Newhall (4), Merit E. Cudkowicz (4), Robert H. Brown Jr. (5) and Robert Bowser (1)

1) Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
2) Center for Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA
3) Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
4) Neurology Clinical Trials Unit, Massachusetts General Hospital East, Charlestown, MA, USA
5) Day Neuromuscular Research Laboratory, Massachusetts General Hospital East, Charlestown, MA, USA Read More

Publication of the Month | February 2006

By The McGowan Institute For Regenerative Medicine | Publication of the Month 2006, Publication of the Month | 0 comment | 30 July, 2015 | 0
Author(s): Hideki Oshima, Thomas R. Payne, Kenneth L. Urish, Tetsuro Sakai, Yiqun Ling, Burhan Gharaibeh, Kimimasa Tobita, Bradley B. Keller, James H. Cummins, and Johnny Huard

Title: Differential Myocardial Infarct Repair with Muscle Stem Cells Compared to Myoblasts

Summary: Myoblast transplantation for cardiac repair has generated beneficial results in both animals and humans; however, poor viability and poor engraftment of myoblasts after implantation in vivo limit their regeneration capacity. We and others have identified and isolated a subpopulation of skeletal muscle-derived stem cells (MDSCs) that regenerate skeletal muscle more effectively than myoblasts. Read More

Publication of the Month | January 2006

By The McGowan Institute For Regenerative Medicine | Publication of the Month 2006, Publication of the Month | 0 comment | 30 July, 2015 | 0
Author(s): Amit N. Patel MD, MS, Luis Geffner MD, Roberto F. Vina MD, Jorge Saslavsky MD, Harold C. Urschel, Jr MD, Robert Kormos MD and Federico Benetti MD

Title: Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: A prospective randomized study. Read More

Publication of the Month | December 2005

By The McGowan Institute For Regenerative Medicine | Publication of the Month 2005, Publication of the Month | 0 comment | 30 July, 2015 | 0
Author: Chuanyue Wu

Title: Migfilin and its binding partners: from cell biology to human diseases

Summary: Links between the plasma membrane and the actin cytoskeleton are essential for maintaining tissue integrity and for controlling cell morphology and behavior. Studies over the past several decades have identified dozens of components of such junctions. One of the most recently identified is migfilin, a widely expressed protein consisting of an N-terminal filamin-binding domain, a central proline-rich domain and three C-terminal LIM domains. Migfilin is recruited to cell-matrix contacts in response to adhesion and colocalizes with beta-catenin at cell-cell junctions in epithelial and endothelial cells. Migfilin also travels from the cytoplasm into the nucleus, a process that is regulated by RNA splicing and calcium signaling. Through interactions with multiple binding partners, including Mig-2, filamin and VASP, migfilin links the cell adhesion structures to the actin cytoskeleton. It regulates actin remodeling, cell morphology and motility. In nuclei, migfilin interacts with the cardiac transcriptional factor CSX/NKX2-5 and promotes cardiomyocyte differentiation. It probably functions as a key regulator both at cell adhesion sites and nuclei, coordinating multiple cellular processes, and is implicated in the pathogenesis of several human diseases. Read More

151617
Print Friendly, PDF & Email
  • site map
  • links
  • contact
  • subscribe to our newsletter
© Copyright 2021 McGowan Institute for Regenerative Medicine
A program of the University of Pittsburgh and the University of Pittsburgh Medical Center
  • Home
  • Our People
    • Faculty/Staff Bios
    • Core Faculty Publications
    • Administrative Resources
  • Our Technologies
  • About Us
    • Welcome
    • Video
    • Mission Statement
    • What Is Regenerative Medicine?
    • Executive Committee
    • Contact Us
    • Clinical Site
  • Our Research
    • Focus Areas
      • Tissue Engineering and Biomaterials
      • Cellular Therapies
      • Medical Devices and Artificial Organs
      • Clinical Translation
    • Matrix
    • Centers
    • Laboratories
    • Clinical Trials
    • Initiatives
  • Media
    • Current News
    • News Archive
    • Video
    • Podcasts
    • Newsletter
    • Grant of the Month
    • Publication of the Month
    • Media Contact
    • Video Links
  • Professional Development
    • Seminar Series
    • Special Events
    • Student Interest Groups
    • CATER
    • Post-Doctoral Opportunities
    • Career Opportunities
    • Wiegand Summer Internship
    • Admissions
    • Summer School
    • 2022 Scientific Retreat
Regenerative Medicine at the McGowan Institute