Han B, Francipane MG, Cheikhi A, Johnson J, Chen F, Chen R, Lagasse E. Fat-associated lymphoid clusters as expandable niches for ectopic liver development. Hepatology. 2022 Aug;76(2):357-371. Epub 2022 Jan 11.

Fontes P, Komori J, Lopez R, Marsh W, Lagasse E. Development of Ectopic Livers by Hepatocyte Transplantation Into Swine Lymph Nodes. Liver Transpl. 2020 Dec;26(12):1629-1643. Epub 2020 Oct 1.

Nicolas CT, Kaiser RA, Hickey RD, Allen KL, Du Z, VanLith CJ, Guthman RM, Amiot B, Suksanpaisan L, Han B, Francipane MG, Cheikhi A, Jiang H, Bansal A, Pandey MK, Garg I, Lowe V, Bhagwate A, O’Brien D, Kocher JA, DeGrado TR, Nyberg SL, Lagasse E, Lillegard JB. Ex Vivo Cell Therapy by Ectopic Hepatocyte Transplantation Treats the Porcine Tyrosinemia Model of Acute Liver Failure. Mol Ther Methods Clin Dev. 2020 Jul 10;18:738-750. eCollection 2020 Sep 11.

Francipane MG, Han B, Lagasse E. Host Lymphotoxin-β Receptor Signaling Is Crucial for Angiogenesis of Metanephric Tissue Transplanted into Lymphoid Sites. American Journal of Pathology. 2020 Jan;190(1):252-269. Epub 2019 Oct 1.

Francipane MG, Han B, Oxburgh L, Sims-Lucas S, Li Z, Lagasse E.Kidney-in-a-lymph node: A novel organogenesis assay to model human renal development and test nephron progenitor cell fates. Journal of Tissue Engineering and Regenerative Medicine. 2019 Sep;13(9):1724-1731. Epub 2019 Jul 30.

Francipane MG, Bulanin D, Lagasse E.  Establishment and Characterization of 5-Fluorouracil-Resistant Human Colorectal Cancer Stem-Like Cells: Tumor Dynamics under Selection Pressure.  International Journal of Molecular Sciences.  2019 Apr 12;20(8). pii: E1817.

Ekser B, Lagasse E.  Interspecies chimeric livers: A step closer to solving the problem of transplantable organ shortage?  Journal of Hepatology.  2018 Nov;69(5):999-1001.  Epub 2018 Sep 14.

Utoh R, Komori J, Kuge H, Tatsumi K, Yamada M, Hirohashi S, Tsutsumi M, Amanuma T, Yoshioka A, Nakajima Y, Wake K, Okano T, Lagasse E, Ohashi K.  Adult hepatocytes direct liver organogenesis through non-parenchymal cell recruitment in the kidney.  Journal of Hepatology.  2018 Apr;68(4):744-753.  Epub 2017 Dec 26.

Iwase H, Liu H, Schmelzer E, Ezzelarab M, Wijkstrom M, Hara H, Lee W, Singh J, Long C, Lagasse E, Gerlach JC, Cooper DKC, Gridelli B.  Transplantation of hepatocytes from genetically engineered pigs into baboons.  Xenotransplantation.  2017 Mar;24(2).  Epub 2017 Jan 28.

Francipane MG, Lagasse E.  Therapeutic potential of mTOR inhibitors for targeting cancer stem cells.  British Journal of Clinical Pharmacology.  2016 Nov;82(5):1180-1188.  Epub 2015 Dec 26.  Review.

Kaseb HO, Fohrer-Ting H, Lewis DW, Lagasse E, Gollin SM.  Identification, expansion and characterization of cancer cells with stem cell properties from head and neck squamous cell carcinomas.  Experimental Cell Research.  2016 Oct 15;348(1):75-86.  Epub 2016 Sep 9.

Francipane MG, Lagasse E.  Regenerating a kidney in a lymph node.  Pediatric Nephrology.  2016 Oct;31(10):1553-60.  Epub 2015 Dec 21.  Review.

Francipane MG, Lagasse E.  Pluripotent Stem Cells to Rebuild a Kidney: The Lymph Node as a Possible Developmental Niche.  Cell Transplantation.  2016;25(6):1007-23.

Keane TJ, DeWard A, Londono R, Saldin LT, Castleton AA, Carey L, Nieponice A, Lagasse E, Badylak SF.  Tissue-Specific Effects of Esophageal Extracellular Matrix.  Tissue Engineering Part A.  2015 Sep;21(17-18):2293-300.

Manohar R, Li Y, Fohrer H, Guzik L, Stolz DB, Chandran UR, LaFramboise WA, Lagasse E.  Identification of a candidate stem cell in human gallbladder.  Stem Cell Research.  2015 May;14(3):258-69.  Epub 2015 Feb 7.

Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JC, Martin MG, Lagasse E, Zhang L, Yu J.  Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation.  Scientific Reports.  2015 Apr 10;5:8566.

Francipane MG, Lagasse E.  The lymph node as a new site for kidney organogenesis.  Stem Cells Translational Medicine.  2015 Mar;4(3):295-307.  Epub 2015 Feb 2.

Cramer JM, Thompson T, Geskin A, LaFramboise W, Lagasse E.  Distinct human stem cell populations in small and large intestine.  PLoS One.  2015 Mar 9;10(3):e0118792.  eCollection 2015.

DeWard AD, Cramer J, Lagasse E.  Cellular heterogeneity in the mouse esophagus implicates the presence of a nonquiescent epithelial stem cell population.  Cell Reports.  2014 Oct 23;9(2):701-11.  Epub 2014 Oct 16.

Cramer JM, Zimmerman MW, Thompson T, Homanics GE, Lazo JS, Lagasse E.  Deletion of Ptp4a3 reduces clonogenicity and tumor-initiation ability of colitis-associated cancer cells in mice.  Stem Cell Research.  2014 Jul;13(1):164-71.  Epub 2014 May 27.

DeWard AD, Komori J, Lagasse E.  Ectopic transplantation sites for cell-based therapy.  Current Opinion in Organ Transplantation.  2014 Apr;19(2):169-74.  Review.

Francipane MG, Lagasse E.  mTOR pathway in colorectal cancer: an update.  Oncotarget.  2014 Jan 15;5(1):49-66.

Komori J, Deward AD, Gramignoli R, Strom SC, Fontes P, Lagasse E.  Potential Barriers to Human Hepatocyte Transplantation in MUP-uPAtg (+/+)Rag2-/-γC-/- Mice.  Cell Transplantation.  2014;23(12):1537-44.  Epub 2013 Aug 30.

Francipane MG, Lagasse E.  Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1.  Oncotarget.  2013 Nov;4(11):1948-62.

Hickey RD, Galivo F, Schug J, Brehm MA, Haft A, Wang Y, Benedetti E, Gu G, Magnuson MA, Shultz LD, Lagasse E, Greiner DL, Kaestner KH, Grompe M.  Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming.  Stem Cell Research.  2013 Jul;11(1):503-15.  Epub 2013 Feb 18.

Komori J, Boone L, DeWard A, Hoppo T, Lagasse E. The mouse lymph node as an ectopic transplantation site for multiple tissues. Nat Biotechnol. 2012 Oct;30(10):976-83. doi: 10.1038/nbt.2379. Epub 2012 Sep 23.  PMID: 23000933

Manohar R, Komori J, Guzik L, Stolz DB, Chandran UR, LaFramboise WA, Lagasse E. Identification and expansion of a unique stem cell population from adult mouse gallbladder. Hepatology. 2011 Nov;54(5):1830-41. doi: 10.1002/hep.24568. PMID: 21793026

Soto-Gutierrez A, Zhang L, Medberry C, Fukumitsu K, Faulk D, Jiang H, Reing J, Gramignoli R, Komori J, Ross M, Nagaya M, Lagasse E, Stolz D, Strom SC, Fox IJ, Badylak SF. A whole-organ regenerative medicine approach for liver replacement. Tissue Eng Part C Methods. 2011 Jun;17(6):677-86. doi: 10.1089/ten.tec.2010.0698. Epub 2011 Apr 20.
PMID: 21375407

Hoppo T, Komori J, Manohar R, Stolz DB, Lagasse E. Rescue of lethal hepatic failure by hepatized lymph nodes in mice. Gastroenterology. 2011 Feb;140(2):656-666.e2. doi:10.1053/j.gastro.2010.11.006. Epub 2010 Nov 9. PMID: 21070777

Chandler JM, Lagasse E. Cancerous stem cells: deviant stem cells with cancer-causing misbehavior. Stem Cell Res Ther. 2010 May 20;1(2):13. doi: 10.1186/scrt13. PMID: 20587011

Manohar R, Lagasse E. Transdetermination: a new trend in cellular reprogramming. Mol Ther. 2009 Jun;17(6):936-8. doi: 10.1038/mt.2009.93. PMID: 19483768

Xiong A, Austin TW, Lagasse E, Uchida N, Tamaki S, Bordier BB, Weissman IL, Glenn JS, Millan MT. Isolation of human fetal liver progenitors and their enhanced proliferation by three-dimensional coculture with endothelial cells. Tissue Eng Part A. 2008 Jun;14(6):995-1006. doi: 10.1089/tea.2007.0087. PMID: 19230124

Teisanu RM, Lagasse E, Whitesides JF, Stripp BR. Prospective isolation of bronchiolar stem cells based upon immunophenotypic and autofluorescence characteristics. Stem Cells. 2009 Mar;27(3):612-22. doi: 10.1634/stemcells.2008-0838. PMID: 19056905

Odoux C, Fohrer H, Hoppo T, Guzik L, Stolz DB, Lewis DW, Gollin SM, Gamblin TC, Geller DA, Lagasse E. A stochastic model for cancer stem cell origin in metastatic colon cancer. Cancer Res. 2008 Sep 1;68(17):6932-41. doi: 10.1158/0008-5472.CAN-07-5779. PMID: 18757407

Omidvar N, Kogan S, Beurlet S, le Pogam C, Janin A, West R, Noguera ME, Reboul M, Soulie A, Leboeuf C, Setterblad N, Felsher D, Lagasse E, Mohamedali A, Thomas NS, Fenaux P, Fontenay M, Pla M, Mufti GJ, Weissman I, Chomienne C, Padua RA. 10. BCL-2 and mutant NRAS interact physically and functionally in a mouse model of progressive myelodysplasia. Cancer Res. 2007 Dec 15;67(24):11657-67. PMID: 18089795

Rajasekhar VK, Dalerba P, Passegué E, Lagasse E, Najbauer J. The 5th International Society for Stem Cell Research (ISSCR) Annual Meeting, June 2007. Stem Cells. 2008 Jan;26(1):292-8. Epub 2007 Oct 25. PMID: 17962698

Iwata A, Stevenson VM, Minard A, Tasch M, Tupper J, Lagasse E, Weissman I, Harlan JM, Winn RK. Over-expression of Bcl-2 provides protection in septic mice by a trans effect. J Immunol. 2003 Sep 15;171(6):3136-41. PMID: 12960340

Wang X, Foster M, Al-Dhalimy M, Lagasse E, Finegold M, Grompe M. The origin and liver repopulating capacity of murine oval cells. Proc Natl Acad Sci U S A. 2003 Sep 30;100 Suppl 1:11881-8. Epub 2003 Aug 5. PMID: 12902545

Jaiswal S, Traver D, Miyamoto T, Akashi K, Lagasse E, Weissman IL. Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):10002-7. Epub 2003 Jul 30. PMID: 12890867

Wang X, Willenbring H, Akkari Y, Torimaru Y, Foster M, Al-Dhalimy M, Lagasse E, Finegold M, Olson S, Grompe M. Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature. 2003 Apr 24;422(6934):897-901. Epub 2003 Mar 30. PMID: 12665832

Austin TW, Lagasse E. Hepatic regeneration from hematopoietic stem cells. Mech Dev. 2003 Jan;120(1):131-5. Review. PMID: 12490303

Wang X, Montini E, Al-Dhalimy M, Lagasse E, Finegold M, Grompe M. Kinetics of liver repopulation after bone marrow transplantation. Am J Pathol. 2002 Aug;161(2):565-74. PMID: 12163381