PI Johnny Huard
Title Tissue Engineered Skeletal Muscle (TESM) from Muscle Progenitor Cells: A Model for Studying Insulin Resistance and Muscle Metabolism
Description The overall specific aims are as follows:
To optimize a protocol for the isolation and differentiation of human MPC
To develop a regimen and bioreactor for development of a tissue engineered skeletal muscle model (TESM) from MPC that will provide a means to study nutrient metabolism and insulin function
To utilize human MPC and the TESM system to analyze pathways involved with glucose homeostasis and fatty acid uptake in healthy and insulin resistant phenotypes
Source Pfizer
Term March 1, 2009 – February 28, 2011
Amount: $475,000