Coronary artery disease is a leading cause of death in the U.S., with about 370,000 Americans dying from the disease each year. Stents are a life-saving procedure used to prop open narrowing blood vessels; however, over time, tissue can regrow into the mesh stent and cause the artery to narrow again, putting the patient at risk.
Knowing as soon as possible that regrowth is happening is crucial in saving the patient’s life, but monitoring is a challenge. McGowan Institute for Regenerative Medicine affiliated faculty member Youngjae Chun, PhD, associate professor of industrial engineering and bioengineering at the University of Pittsburgh’s Swanson School of Engineering, has received a funding award from the American Heart Association for his project creating a stent that will use sensors to monitor for signs of restenosis and alert the patient’s doctor without the need for endless follow-up visits.
Dr. Chun’s project has been selected by the American Heart Association for its 2019 Innovative Project Award, which supports highly innovative, high-impact research that could lead to major advancements and discoveries that accelerate cardiovascular and cerebrovascular research. The award includes a total of $200,000 over two years and began on July 1, 2019.
“Stenting to treat coronary artery disease is a well-established and widely used interventional procedure. This new stent will minimize the follow-up imaging procedures that can be inconvenient, expensive, and sometimes invasive for the patient,” says Dr. Chun. “Our device would continuously monitor restenosis providing valuable information to the patients.”
This project will be conducted through a multidisciplinary collaboration with W. Hong Yeo, PhD, assistant professor of Department of Mechanical Engineering at Georgia Tech, and McGowan Institute affiliated faculty member John Pacella, MD, cardiologist at UPMC.
“Real-time surveillance would be critical for the patient whose stented blood vessels are re-narrowing, putting them at risk for heart attack or stroke,” says Dr. Chun. “The device would provide critical information directly to patients and their doctors and could potentially save many lives.”