Method For Inhibiting Osteoclast Development
Inventors: Harry Colbert Blair: John B. Barnett Ph.D.: Rosana Schafer: Jonathan Soboloff Ph.D.
Patent Number: 13/864,438
Abstract
This invention provides a composition comprising Formula I, or salt thereof,
![](https://patentimages.storage.googleapis.com/c0/b5/6f/27719cb253b26f/US20130303621A1-20131114-C00001.png)
wherein X is either chlorine or bromine, Y is either hydrogen or an alkyl group having a carbon chain length from 1 to 5 carbon atoms, and R is an alkyl group having a carbon chain length from 1 to 5 carbon atoms, except that X is not chlorine when Y is hydrogen and R is an ethyl group. A method of preventing bone erosion in a patient and a method of reducing inflammation in a patient using the compositions of Formula I are disclosed.
![](https://patentimages.storage.googleapis.com/c0/b5/6f/27719cb253b26f/US20130303621A1-20131114-C00001.png)
wherein X is either chlorine or bromine, Y is either hydrogen or an alkyl group having a carbon chain length from 1 to 5 carbon atoms, and R is an alkyl group having a carbon chain length from 1 to 5 carbon atoms, except that X is not chlorine when Y is hydrogen and R is an ethyl group. A method of preventing bone erosion in a patient and a method of reducing inflammation in a patient using the compositions of Formula I are disclosed.