Method For Inhibiting Osteoclast Development

Inventors: Harry Colbert Blair: John B. Barnett Ph.D.: Rosana Schafer: Jonathan Soboloff Ph.D.

Patent Number: 13/864,438

Abstract

This invention provides a composition comprising Formula I, or salt thereof,

wherein X is either chlorine or bromine, Y is either hydrogen or an alkyl group having a carbon chain length from 1 to 5 carbon atoms, and R is an alkyl group having a carbon chain length from 1 to 5 carbon atoms, except that X is not chlorine when Y is hydrogen and R is an ethyl group. A method of preventing bone erosion in a patient and a method of reducing inflammation in a patient using the compositions of Formula I are disclosed.
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