Disclosed is a device and method for acquiring a fusion image, which applies an ultrasound signal for an ultrasound image, an optical signal for a photoacoustic image and a fluorescent image to a target, receives an ultrasound signal, a photoacoustic signal and an optical signal from the target, and generates a fusion image including image information with different probing planes with respect to the target by using at least two signals of the received ultrasound signal, the received photoacoustic signal and the received optical signal.