Use Of Relaxin To Increase Arterial Compliance (2)

Patient/Subject Is Having A Disease Selected From One Or More Of Atherosclerosis, Type 1 Diabetes, Type 2 Diabetes, Coronary Artery Disease, Scleroderma, Stroke, Diastolic Dysfunction, Hypercholesterolemia, Familial Hypercholesterolemia, Isolated Systolic Hypertension, Primary Hypertension, Secondary Hypertension, Left Ventricular Hypertrophy, Arterial Stiffness Associated With Long-Term Tobacco Smoking, Arterial Stiffness Associated With Obesity, And/Or Arterial Stiffness Associated With Age And Systemic Lupus Erythematosis

Inventors: Sanjeev G. Shroff PhD: Kirk Conrad

Patent Number: 14/071,705

Abstract

The present invention provides methods for increasing arterial compliance. The methods generally involve administering to an individual in need thereof an effective amount of relaxin. The present invention further provides methods of increasing arterial compliance in individuals who have Type 1 or Type 2 diabetes. The present invention further provides methods of increasing arterial compliance in perimenopausal, menopausal, and post-menopausal women. The present invention further provides methods of increasing arterial compliance in individuals who have or who are at risk of developing age-associated arterial stiffness.
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