Project Description

Thermoresponsive Hydrogel Containing Polymer Microparticles For Noninvasive Ocular Biologic Delivery

Inventors: Morgan Virginia Fedorchak: Joel Steven Schuman: Steven R. Little

Patent Number: PCT/US2017/023455


A method for sustained delivery of an agent to an ocular organ in a subject, comprising topically delivering to the ocular surface a liquid thermoresponsive hydrogel comprising agent-loaded polymer microparticles, wherein the agent is an antibody, a fusion protein, a chemokine, an interleukin, a growth factor, albumin, immunoglobulin, an interferon, a peptide, stem cell-conditioned media, plasma or serum.
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