Particle Formulations Of All-Trans Retinoic Acid And Transforming Growth Factor Beta For The Treatment Of Type 1 Diabetes Mellitus
Inventors: Nick Giannoukakis: Wilson S. Meng: Massimo M. Trucco
Patent Number: 10,105,334
Abstract
Particle formulations are disclosed that include polymeric particles containing a small molecule drug and a high molecular weight therapeutic protein. Methods of making and using the particle formulations also are disclosed. These particle formulations are of use to treat an autoimmune disease, such as diabetes, or an inflammatory disease.