Particle Formulations Of All-Trans Retinoic Acid And Transforming Growth Factor Beta For The Treatment Of Type 1 Diabetes Mellitus

Inventors: Nick Giannoukakis: Wilson S. Meng: Massimo M. Trucco

Patent Number: 15/112,152

Abstract

Particle formulations are disclosed that include polymeric particles containing a small molecule drug and a high molecular weight therapeutic protein. Methods of making and using the particle formulations also are disclosed. These particle formulations are of use to treat an autoimmune disease, such as diabetes, or an inflammatory disease.
View Google Patent Page
Download PDF