Method Of Manufacturing Hydroxyapatite And Uses Therefor In Delivery Of Nucleic Acids

Method For Making A Hydroxyapatite Complex, Comprising Reacting Calcium Ions With Na3po4 In The Presence Of Hydroxyl Ions And A Biomolecule

Inventors: Jeffrey O. Hollinger: Daiwon Choi: Charles Sfeir: Prashant Kumta: Phil Campbell: Lee Weiss

Patent Number: 11/811,992

Abstract

Provided is a method for production of nanocrystalline hydroxyapatite particles, and nanocrystalline hydroxyapatite particles produced according to the method. The nanocrystalline hydroxyapatite particles exhibit substantially superior cell transformation abilities as compared to known and commercially-available calcium phosphate kits. The nanocrystalline hydroxyapatite particles also find use in tissue engineering applications, for example bone and tooth engineering and repair applications.
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