Method Of Manufacturing Hydroxyapatite And Uses Therefor In Delivery Of Nucleic Acids (2)
Method for Making Hydroxyapatite, Comprising the Step of Reacting Calcium Ions with Phosphate Ions in the Presence of Hydroxyl Ions, wherein the Ratio of Calcium Ions to Phosphate Ions is Greater than 1.67
Inventors: Jeffrey O Hollinger: Daiwon Choi: Charles Sfeir: Prashant Kumta: Phil Campbell: Lee Weiss
Patent Number: 10/393,507
Abstract
Provided is a method for production of nanocrystalline hydroxyapatite particles, and nanocrystalline hydroxyapatite particles produced according to the method. The nanocrystalline hydroxyapatite particles exhibit substantially superior cell transformation abilities as compared to known and commercially-available calcium phosphate kits. The nanocrystalline hydroxyapatite particles also find use in tissue engineering applications, for example bone and tooth engineering and repair applications.
