Method for Engineering Three-Dimensional Synthetic Vascular Networks through Mechanical Micromachining and Mutable Polymer Micromolding
Inventors: Yadong Wang: Donna B. Stolz: Philip LeDuc: O. Burak Ozdoganlar Ph.D.: Mary E. Wilson: Emrullah Korkmaz
Patent Number: 14/750,620
The present invention relates generally to a method that is used to create three-dimensional synthetic vascular networks. Micromachining and molding techniques are used to create a template in a shape that mimics a biological network. Cellular material can be seeded around the template or a space created by the template and grown into an engineered tissue-construct.