Method For Diagnosis, Prognosis, And Determination For Cutaneous T-Cell Lymphoma

Inventors: Brittany L. O. Dulmage: Larisa J. Geskin: Louis D. Falo Jr

Patent Number: 14/819,950

Abstract

The present invention relates to biomarkers associated with CTCL, including TOX, PLS3, KIR3DL2, GATA3 and RUNX3, where increased expression, relative to normal control, of one or more of TOX, PLS3, KIR3DL2, and/or GATA3 is associated with CTCL and decreased expression of RUNX3, relative to normal control, is associated with CTCL. One or more of these biomarkers may be used to diagnose CTCL and/or design and monitor treatment.
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