Extracellular Matrix-Derived Gels And Related Methods

Focused On Composition Comprising: (A) Extracellular Matrix Derived From A Mammalian Tissue And (B) An Acid Protease

Inventors: Stephen F. Badylak: Donald O. Freytes

Patent Number: 14/182,791

Abstract

Provided are methods for preparing gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth scaffolds. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.
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