Project Description

Complex Coacervate For Controlled Release And Related Methods

Inventors: Yadong Wang: Eric M. Jeffries

Patent Number: PCT/US2016/066640

Abstract

Provided herein are coacervate compositions including cytokines, and methods of making and using the same. The coacervate can be formed by the mixing of an active agent, such as a drug or protein with the polyanion, such as heparin or heparan sulfate, and a custom-made polycation (e.g., PEAD or PELD). The coacervates can be used in the treatment of diseases and disorders where targeted treatment is desired, for example in treatment of cancers.
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