Bioerodible Wraps And Uses Therefor (4)

Tubular Tissue Graft Device Comprising: A Tubular Tissue Having A Wall Defining A Lumen, The Lumen Extending From A First End Of The Tubular Tissue To A Second End Of The Tubular Tissue

Inventors: Mohammed Salim El-Kurdi: David Alan Vorp Ph.D.: William R. Wagner PhD: Yi Hong: John J. Stankus: Lorenzo Soletti: J Christopher Flaherty: Jonathan McGrath

Patent Number: 13/502,759

Abstract

A tubular tissue graft device is provided comprising a tubular member and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. 5 Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
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