TRPV1 Modulatory Gene Product That Affects TRPV1-Specific Pain Behavioral Responses Identified In A Functional Screen Of An HSV-Based cDNA Library (2)
Expression Cassette Comprises A Nucleic Acid Sequence Encoding Pp1α
Inventors: William F. Goins Ph.D.: Joseph C. Glorioso III: Justus Bernhard Cohen: Bonnie L. Reinhart
Patent Number: 15/442,521
Abstract
The invention provides a method for ameliorating chronic pain signaling involving transient receptor potential cation channel subfamily V member 1 (TRPV1) by expressing PP1α in neurons. The invention also provides HSV vectors for expressing PP1α within neurons and compositions comprising such vectors.
