ECM Therapeutics is a regenerative medicine company that develops and manufactures diagnostic and therapeutic products derived from a naturally occurring material called extracellular matrix (ECM).
Clinical Challenge
Cell-based and drug-based approaches for tissue and organ replacement have not met the hopes and expectations of the medical community or the patients in need of such therapies. The reasons are numerous, but the common theme is the failure of cells and engineered tissues to survive following implantation in the patient. An effective strategy to overcome this barrier represents an opportunity to address several serious unmet medical needs and change the practice of medicine.
Technology Solution
Naturally occurring biologic materials composed of extracellular matrix (ECM) have been successfully used for almost 20 years as surgical meshes and topical wound products. ECM Therapeutics has developed a hydrogel form of ECM that represents Mother Nature’s version of the ideal “niche” in which cells thrive. The ECM hydrogel promotes a number of constructive wound healing events including: 1) the mobilization and differentiation of the body’s local stem cells, 2) the transformation of the immune system from a pro-inflammatory phenotype to an anti-inflammatory, tissue healing phenotype, and 3) the suppression of abnormal signaling pathways within pre-cancerous and cancer cells. The ECM hydrogel represents a solution to many potential serious medical problems. The first products target esophageal and colorectal disease.
For the most recent news about ECM Therapeutics, please visit www.ecmtherapeutics.com