{"id":418,"date":"2019-10-03T21:08:56","date_gmt":"2019-10-03T21:08:56","guid":{"rendered":"https:\/\/mirm-pitt.net\/technologies\/?p=418"},"modified":"2019-10-03T21:08:56","modified_gmt":"2019-10-03T21:08:56","slug":"neurogel-injectable-hydrogel-for-peripheral-nerve-reconstruction","status":"publish","type":"post","link":"https:\/\/mirm-pitt.net\/technologies\/2019\/10\/03\/neurogel-injectable-hydrogel-for-peripheral-nerve-reconstruction\/","title":{"rendered":"NeuroGel: Injectable Hydrogel for Peripheral Nerve Reconstruction"},"content":{"rendered":"

Paul Gardner, MD<\/a>, <\/strong>Clinical PI
\n<\/em>Associate Professor of Neurological Surgery<\/p>\n

Email:\u00a0<\/strong>pagst28@pitt.edu\u00a0<\/a>
\nPhone:<\/strong> (412) 802-8259<\/p>\n

Bryan Brown, PhD<\/a>, <\/strong>Scientific PI
\n<\/em>Assistant Professor of Bioengineering<\/p>\n

Email:<\/strong>bnb9@pitt.edu<\/a>
\nPhone:<\/strong> (412) 624-5273<\/p>\n

Travis Prest, MS, <\/strong>PhD,<\/strong> Graduate Student<\/em><\/p>\n

Email:\u00a0<\/strong>tap56@pitt.edu\u00a0<\/a>
\nPhone:<\/strong> (412) 648-7875<\/p>\n

In the U.S., more than 900,000 procedures per year are performed to address traumatic and surgical nerve injuries, representing a $1.68 billion market. While there are currently a variety of devices such as conduits, wraps, and sponges that are used to try to bridge transected nerves, most have shown only limited benefit. As a result, surgeons prefer to use nerve autografts where possible, despite the potential for permanent loss of sensation at the donor site. But even these grafts have shown limited success. NeuroGel provides a new regenerative matrix that promotes healing of the original nerve tissue. Neurogel is composed of a solution of nerve-specific structural and functional components that are present in normal healthy nerves, and obtained through a proprietary decellularization and enzymatic treatment process. In pre-clinical studies, injection of NeuroGel at the site of a transected nerve has been shown to speed recovery and improve nerve regeneration. To-date, three preclinical animal studies have been performed that have demonstrated that NeuroGel is more effective than traditional approaches in a number of nerve injury scenarios, including end-to-end nerve repair, nerve gap repair, and nerve graft support.<\/p>\n","protected":false},"excerpt":{"rendered":"

Paul Gardner, MD, Clinical PI Associate Professor of Neurological Surgery […]<\/p>\n","protected":false},"author":1,"featured_media":419,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[39],"tags":[],"_links":{"self":[{"href":"https:\/\/mirm-pitt.net\/technologies\/wp-json\/wp\/v2\/posts\/418"}],"collection":[{"href":"https:\/\/mirm-pitt.net\/technologies\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mirm-pitt.net\/technologies\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mirm-pitt.net\/technologies\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mirm-pitt.net\/technologies\/wp-json\/wp\/v2\/comments?post=418"}],"version-history":[{"count":1,"href":"https:\/\/mirm-pitt.net\/technologies\/wp-json\/wp\/v2\/posts\/418\/revisions"}],"predecessor-version":[{"id":420,"href":"https:\/\/mirm-pitt.net\/technologies\/wp-json\/wp\/v2\/posts\/418\/revisions\/420"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mirm-pitt.net\/technologies\/wp-json\/wp\/v2\/media\/419"}],"wp:attachment":[{"href":"https:\/\/mirm-pitt.net\/technologies\/wp-json\/wp\/v2\/media?parent=418"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mirm-pitt.net\/technologies\/wp-json\/wp\/v2\/categories?post=418"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mirm-pitt.net\/technologies\/wp-json\/wp\/v2\/tags?post=418"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}