{"id":3056,"date":"2020-06-04T18:35:14","date_gmt":"2020-06-04T18:35:14","guid":{"rendered":"https:\/\/mirm-pitt.net\/technologies\/?post_type=avada_portfolio&p=3056"},"modified":"2020-07-08T09:11:53","modified_gmt":"2020-07-08T09:11:53","slug":"reverse-thermal-gels-and-their-use-in-cell-therapy","status":"publish","type":"avada_portfolio","link":"https:\/\/mirm-pitt.net\/technologies\/patents\/reverse-thermal-gels-and-their-use-in-cell-therapy\/","title":{"rendered":"Reverse Thermal Gels And Their Use In Cell Therapy"},"content":{"rendered":"

Reverse Thermal Gels And Their Use In Cell Therapy<\/h2>\n<\/div>
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Inventors:<\/strong> Yadong Wang: Martin Oudega<\/p>\n

Patent Number:<\/strong> 14\/459,178<\/p>\n

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Abstract<\/h3>\n
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Methods are disclosed herein for increasing survival of transplanted cells, either in vitro or in vivo. In additional embodiments, methods are disclosed for treating a subject with a spinal cord injury or a neurodegenerative disorder. The methods include administering to a subject a therapeutically effective amount of cells, such as bone marrow stromal cells, and a therapeutically effective amount of a reverse thermal gel composition. The reverse thermal gel compositing includes a triblock copolymer, or pharmaceutically acceptable salt thereof, having the structure B-A-B in which A is one of a polyurethane or poly(ester urethane) group that comprises one or more pendant active groups, blocked active groups or active agents and B is a hydrophilic block, wherein the composition is a gel at 25\u00b0 C.-40\u00b0 C. and a liquid solution at a lower temperature.<\/div>\n<\/section>\n<\/div>\n<\/section>\n<\/div>\n<\/div>\n<\/div>
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