{"id":2719,"date":"2020-06-01T17:32:02","date_gmt":"2020-06-01T17:32:02","guid":{"rendered":"https:\/\/mirm-pitt.net\/technologies\/?post_type=avada_portfolio&p=2719"},"modified":"2020-07-08T09:19:24","modified_gmt":"2020-07-08T09:19:24","slug":"compositions-for-modulating-an-xbp1-pathway-in-a-keratinocyte-and-methods-of-use","status":"publish","type":"avada_portfolio","link":"https:\/\/mirm-pitt.net\/technologies\/patents\/compositions-for-modulating-an-xbp1-pathway-in-a-keratinocyte-and-methods-of-use\/","title":{"rendered":"Compositions For Modulating An XBP1 Pathway In A Keratinocyte And Methods Of Use"},"content":{"rendered":"

Compositions For Modulating An XBP1 Pathway In A Keratinocyte And Methods Of Use<\/h2>\n<\/div>
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Inventors:<\/strong> Louis D. Falo Jr: Zhaoyang You<\/p>\n

Patent Number:<\/strong> PCT\/US2016\/039265<\/p>\n

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Abstract<\/h3>\n
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Provided herein are compositions and methods for increasing an immune response in a subject, immunizing a subject and\/or treating a disease in a subject that relate to keratinocytes. It is a surprising finding of the present invention that modulation of an XBP1 pathway creates a keratinocyte that is itself an immune modulator, or adjuvant. In some embodiments, the concentration of antigen is increased in the vicinity of the keratinocyte, further increasing the immune response by effector cells within that vicinity.<\/div>\n<\/section>\n<\/div>\n<\/section>\n<\/div>\n<\/div>\n<\/div>
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