{"id":1396,"date":"2020-05-12T20:19:15","date_gmt":"2020-05-12T20:19:15","guid":{"rendered":"https:\/\/mirm-pitt.net\/technologies\/?post_type=avada_portfolio&p=1396"},"modified":"2020-07-08T05:38:33","modified_gmt":"2020-07-08T05:38:33","slug":"methods-of-electrospinning-and-compositions-made-therefrom","status":"publish","type":"avada_portfolio","link":"https:\/\/mirm-pitt.net\/technologies\/patents\/methods-of-electrospinning-and-compositions-made-therefrom\/","title":{"rendered":"Methods Of Electrospinning And Compositions Made Therefrom"},"content":{"rendered":"

Methods Of Electrospinning And Compositions Made Therefrom<\/h2>\n<\/div>
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Inventors:<\/strong> Eric M. Jeffries: Yadong Wang: Robert A. Allen<\/p>\n

Patent Number:<\/strong> 14\/652,744<\/p>\n

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Abstract<\/h3>\n
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Disclosed herein are methods of electrospinning poly(glycerol sebacate) (PGS) which allow stable PGS fibers and fibrous PGS constructs, scaffolds and grafts to be formed. In one example, a disclosed method includes generating PGS fibers by blending PGS prepolymer with a heat resistant synthetic carrier polymer, wherein the blend is electrospun into micro-or nano-fibers, and the PGS prepolymer is cross-linked into PGS with heat without using chemical cross-linkers. In another example, a disclosed method includes electrospinning a PGS and gelatin blend, wherein the PGS and gelatin composition are cross-linked by heat curing without using chemical cross-linkers. In another example, the method includes preparing an electrospinning precursor solution comprising blending PGS prepolymer with with poly(lactic-co-glycolic acid) (PLGA) and a chemical cross-linker; electrospinning the prepared blend; and exposing the electrospun blend to an organic solvent to remove the PLGA.<\/div>\n<\/section>\n<\/div>\n<\/section>\n<\/div>\n<\/div>\n<\/div>
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