{"id":1110,"date":"2020-05-06T19:48:58","date_gmt":"2020-05-06T19:48:58","guid":{"rendered":"https:\/\/mirm-pitt.net\/technologies\/?post_type=avada_portfolio&p=1110"},"modified":"2020-07-09T12:23:19","modified_gmt":"2020-07-09T12:23:19","slug":"fractionating-extracellular-matrix-to-modulate-bioactivity-and-the-host-response","status":"publish","type":"avada_portfolio","link":"https:\/\/mirm-pitt.net\/technologies\/patents\/fractionating-extracellular-matrix-to-modulate-bioactivity-and-the-host-response\/","title":{"rendered":"Fractionating Extracellular Matrix to Modulate Bioactivity and the Host Response"},"content":{"rendered":"

Fractionating Extracellular Matrix to Modulate Bioactivity and the Host Response<\/h2>\n<\/div>
<\/div><\/div><\/div>

Inventors:<\/strong> Stephen Francis Badylak DVM, PhD, MD: Peter F. Slivka<\/p>\n

Patent Number:<\/strong> 15\/306,262<\/p>\n

\n
\n
\n

Abstract<\/h3>\n
\n
\n
\n
\n
Provided herein are methods of fractionating extracellular matrix (ECM) materials, producing soluble and structural fractions having different immunological activities. Also provided are compositions and devices comprising the fractions. A method of immune modulation also is provided in which an amount of a soluble or structural ECM fraction prepared according to the methods provided herein is administered to a patient in an amount effective to modulate immune function, for example macrophage function.<\/div>\n<\/section>\n<\/div>\n<\/section>\n<\/div>\n<\/section>\n<\/div>\n<\/div>\n<\/div>
<\/div>
<\/div>
<\/div>