Dr. Zachary Freyberg is an Assistant Professor in the Departments of Psychiatry and Cell Biology (secondary). He is also an Associate Member of the Pittsburgh Liver Research Center.
Dr. Freyberg received his MD in Medicine from the Albert Einstein College of Medicine, Bronx, NY. He received his PhD in Developmental & Molecular Biology also from Albert Einstein College of Medicine. It was at New York Presbyterian Hospital – Weill Cornell Medical Center, New York, NY, where he finished an Internship in Internal Medicine, Neurology & Psychiatry and a Residency in Psychiatry (Payne Whitney Clinic). Dr. Freyberg then completed a Fellowship in Schizophrenia Research at Columbia University/New York State Psychiatric Institute, New York, NY.
The overall long-term goal of Dr. Freyberg’s research is to better understand human disorders of dopaminergic neurotransmission including addiction, schizophrenia and Parkinson’s disease. In order to do so, his laboratory has begun dissecting presynaptic dopaminergic neurotransmission at the synaptic vesicle level using a combination of complementary approaches including genetics, pharmacology and both light and electron microscopy. Consequently, the lab’s current research projects include:
Mechanisms of Dopamine Synaptic Vesicle Loading and Release.
Dopamine’s Role in Regulation of Insulin Release and Antipsychotic Drug Action.
In Situ Cryo-Electron Microscopy Approaches to Investigation of Vesicle Trafficking.
In Situ Cryo-Electron Microscopy Approaches to Clinical Medicine.
Dr. Freyberg holds professional affiliations with these organizations:
Society for Neuroscience
Genetics Society of America
Schizophrenia International Research Society
International Transmembrane Transporter Society
Society of Biological Psychiatry
In 2019, Dr. Freyberg was honored with the A.E. Bennett Award for Basic Research, Society of Biological Psychiatry, and the Hamilton Family Award for Basic Research in Psychiatry.
View a list of Dr. Freyberg’s publications here.