Thottala Jayaraman, PhD

Dr. Thottala Jayaraman is an Associate Professor in the Department of Oral Biology in the School of Dental Medicine at the University of Pittsburgh.  He received his PhD in immunology from All India Institute of Medical Sciences, New Delhi, India. After completing his post-doctoral fellowships at Yale University and Mount Sinai Medical Center, he joined Columbia University faculty as an Assistant Professor in the Department of Medicine. In addition, he also held joint appointments as an Associate Director of Vascular Biology Research Program and an Assistant Professor of Neurosurgery at St. Luke’s Roosevelt Hospital Center in New York before joining the University of Pittsburgh. Dr. Jayaraman’s research is focused on three specific areas: 1) the regulation of acidic phosphoproteins by phosphorylation during bio-mineralization in dentin and bone; 2) the role of calcium binding phospholipids in vascular calcification; and 3) the role of intracellular calcium in pancreatitis. While intra- and extracellular lipids appear to play an important role in both physiological and pathological processes, detailed information on the calcium binding bioactive lipids in mineralizing cell types would advance our understanding of their role in bone and dentine formation. Dr. Jayaraman serves as a Reviewer for several journals, namely, the Journal of Dental Research, the International Journal of Biological Macromolecules, Scientific Reports and the Journal of Neurological Sciences. View a list of Dr. Jayaraman’s publications here.