Thottala Jayaraman, PhD

Dr. Thottala Jayaraman is an Assistant Professor in the Department of Oral Biology in the School of Dental Medicine at the University of Pittsburgh.  He received his PhD in immunology from the All India Institute of Medical Sciences, New Delhi, India. After completing his post-doctoral fellowships at Yale University and Mount Sinai Medical Center, he joined Columbia University faculty as an Assistant Professor in the Department of Medicine. In addition, he also held joint appointments as an Associate Director of Vascular Biology Research Program and an Assistant Professor of Neurosurgery at St. Luke’s Roosevelt Hospital Center in New York before joining the University of Pittsburgh. Dr. Jayaraman’s research is focused on two specific research areas: 1) the regulation of acidic phosphoproteins during bio-mineralization; and 2) the regulation of calcium binding proteins and lipids that are involved in pathological mineralization. While lipids, intra- and extracellular, appear to play an important role in both physiological and pathological processes, detailed information on the bioactive lipids that modulate calcium-signaling pathways in mineralizing cell types would advance our understanding of their role in bone and dentine formation. Dr. Jayaraman serves as a Reviewer for several journals, namely, the Journal of Dental Research, the International Journal of Biological Macromolecules, Scientific Reports and the Journal of Neurological Sciences. View a list of Dr. Jayaraman’s publications here.