Steffi Oesterreich, PhD
Steffi Oesterreich, PhD
Dr. Steffi Oesterreich is a Professor of Pharmacology and Chemical Biology at the University of Pittsburgh Cancer Institute. She is also the Director of Education at the Women's Cancer Research Center, a collaboration between the Magee Women's Research Institute and University of Pittsburgh Cancer Institute. In addition, Dr. Oesterreich is a Graduate Faculty Member of the Interdisciplinary Biomedical Graduate Program in Molecular Pharmacology and in Molecular Pathology at the University of Pittsburgh School of Medicine.
Dr. Oesterreich received her BS in Biochemistry at the Humboldt University, Berlin, Germany, in 1989. In 1992, she received her PhD in Molecular Medicine from the Humboldt University, Max-Delbrück Center for Molecular Medicine, Berlin, Germany. Post-graduation, she participated in a Fellowship in Breast Cancer at the University of Texas Health Science Center in San Antonio, Texas, and spent some time in Germany as an Alexander-von-Humboldt-Fellow.
A list of Dr. Oesterreich’s current research interests includes:
- Endocrine treatment resistance in breast cancer
- Novel targets
- Genetic (e.g. SNPs) and epigenetic (e.g. DNA methylation, histone modifications) changes causatively associated with resistance
- Invasive Lobular Cancer (ILC)
- Transition from LCIS to ILC
- Unique properties of ILC (compared to IDC)
- Hormone response in ILC
- Clinical relevance and mechanism of action of:
- Coregulator proteins
- Estrogen receptor
- Crosstalk between steroid receptor and growth factor signaling
- Hormone response in ovarian cancer