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Gary (Hin-Fai) Yam, PhD

    Home Faculty/Staff Bios Gary (Hin-Fai) Yam, PhD

    Gary (Hin-Fai) Yam, PhD

    Dr. Gary Yam is a Research Associate Professor of Ophthalmology, Corneal Regeneration Laboratory, University of Pittsburgh School of Medicine. Dr. Yam attended the Chinese University of Hong Kong where he obtained his Doctor of Philosophy (PhD) in Oncology and Cancer Biology, Master's degree in Oncology and Cancer Biology, and Bachelor’s degree in Biology, General. Dr. Yam’s research interests include cell biology: corneal epithelium and stromal keratocytes and application in cell-based therapy for ocular surface disorders; stromal tissue engineering and bioscaffold: cell-tissue construct and applications; cell therapy for treatment of ocular defects; cell reprogramming and transdifferentiation; epigenetics; protein folding disorders and molecular chaperone-assisted protein refolding. The Cornea Regeneration Lab focuses on the cornea, an organ that provides a visual portal to the world. The connective tissue of cornea (stroma) is extremely tough, and transparent to light. It also presents a significant biological barrier to infection. Globally, millions of patients have corneal opacification due to disease or trauma, hence vision loss. Dr. Yam’s work focuses on the biological processes that produce and maintain the unique tissue of corneal stroma as well as the pathological changes that occur during injury, wound healing, scarring and diseases. He and his team explore new designs to reverse the scarring process or replace the scarred cornea with bioengineered corneal tissue. Their lab has reported the use of stromal keratocytes and stromal stem cells to restore corneal transparency. These cell-based treatments produce tissue identical to that of the transparent corneal stromal tissue in animal models of corneal injury. Dr. Yam and others are developing GMP compliant Standard Operating Procedures for clinical trials in patients with corneal scarring, and also actively investigating the mechanism by which the stem cells induce tissue regeneration. View a list of Dr. Yam’s publications here.
    Name:
    Dr. Gary Yam
    Website:
    (412) 647-3853
    Email:
    gary.yam@pitt.edu
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    • Home
    • Our People
      • Faculty/Staff Bios
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      • Administrative Resources
    • Our Technologies
    • About Us
      • Welcome
      • Video
      • Mission Statement
      • What Is Regenerative Medicine?
      • Executive Committee
      • Contact Us
      • Clinical Site
    • Our Research
      • Focus Areas
        • Tissue Engineering and Biomaterials
        • Cellular Therapies
        • Medical Devices and Artificial Organs
        • Clinical Translation
      • Matrix
      • Centers
      • Laboratories
      • Clinical Trials
      • Initiatives
    • Media
      • Current News
      • News Archive
      • Video
      • Podcasts
      • Newsletter
      • Grant of the Month
      • Publication of the Month
      • Media Contact
      • Video Links
    • Professional Development
      • Seminar Series
      • Special Events
      • Student Interest Groups
      • CATER
      • Post-Doctoral Opportunities
      • Career Opportunities
      • Wiegand Summer Internship
      • Admissions
      • Summer School
      • 2022 Scientific Retreat
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