PI Alan J. Russell, Stephen F. Badylak, J. Peter Rubin, Bernard J. Costello, Prashant N. Kumta, Charles Sfeir, Paul Kemp

Title Limb Salvage and Regenerative Medicine Initiative

Co-Investigators Thomas Gilbert

Description This program will advance technologies that return wounded personnel to active duty, restore their limb, muscular, and skin form or function, and assist them in reclaiming independence, dignity, and self-confidence in the tasks of daily living. The program will fund rapid research, development and validation of innovative technologies to improve the clinical outcome of burn and blast injured personnel. Technology refers to integrated systems based on combinations of hardware, software, pharmaceuticals, biologics, and surgical methods. This initiative will advance medical technologies from their existing levels of maturation, through FDA trials and approval, to significantly improve upon current standard treatments for use by the Department of Defense, Veteran’s Administration, public health, and commercial health systems.

Program Areas:
1) Muscle Tissue Regeneration with the Use of Biologic Scaffolds for Patients Suffering from Massive Loss of Skeletal Muscle Tissue

2) Bone Scaffolding for Craniofacial Regeneration

3) Research and Implementation of Clinical Trials of Allogenic Human Dermal Fibroblasts for Remodeling Scar contractors using ICX-RHY Technology

Source DOD

Term 04/01/10-3/31/12

Amount: $12,183,808